LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 10.60 | 19.50 | 402 | 467 | 0.8609 | 0.5405 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 12.50 | 19.50 | 424 | 495 | 0.8572 | 0.5691 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 14.50 | 19.50 | 445 | 537 | 0.8274 | 0.6311 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 16.50 | 19.50 | 479 | 626 | 0.7718 | 0.6839 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 18.40 | 19.50 | 534 | 775 | 0.6954 | 0.7330 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 20.40 | 19.50 | 603 | 951 | 0.6448 | 0.7600 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 22.40 | 19.50 | 664 | 1150 | 0.5852 | 0.7486 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 24.30 | 19.50 | 733 | 1322 | 0.5499 | 0.7465 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 26.30 | 19.50 | 761 | 1491 | 0.5081 | 0.7360 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 28.30 | 19.50 | 759 | 1665 | 0.4548 | 0.7121 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 30.30 | 19.50 | 781 | 1887 | 0.4140 | 0.6953 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 32.20 | 19.50 | 791 | 2123 | 0.3737 | 0.6780 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 34.20 | 19.50 | 820 | 2452 | 0.3375 | 0.6642 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 36.20 | 19.50 | 840 | 2641 | 0.3195 | 0.6568 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 38.10 | 19.50 | 839 | 2867 | 0.2939 | 0.6430 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 40.10 | 19.50 | 845 | 3104 | 0.2727 | 0.6322 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 42.10 | 19.50 | 859 | 3461 | 0.2489 | 0.6188 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 44.00 | 19.50 | 868 | 3824 | 0.2281 | 0.6071 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 46.00 | 19.50 | 866 | 4146 | 0.2088 | 0.5947 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 48.00 | 19.50 | 877 | 4441 | 0.1971 | 0.5877 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 50.00 | 19.50 | 874 | 4744 | 0.1837 | 0.5775 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 51.90 | 19.50 | 884 | 4974 | 0.1768 | 0.5743 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 53.90 | 19.50 | 881 | 5154 | 0.1695 | 0.5689 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 55.90 | 19.50 | 897 | 5348 | 0.1663 | 0.5672 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 57.80 | 19.50 | 887 | 5483 | 0.1601 | 0.5631 |