LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 36.20 | 19.50 | 873 | 2641 | 0.3313 | 0.5643 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 38.10 | 19.50 | 934 | 2867 | 0.3268 | 0.5776 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 40.10 | 19.50 | 974 | 3104 | 0.3141 | 0.5769 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 42.10 | 19.50 | 1023 | 3461 | 0.2962 | 0.5709 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 44.00 | 19.50 | 1081 | 3824 | 0.2834 | 0.5671 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 46.00 | 19.50 | 1126 | 4146 | 0.2717 | 0.5687 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 48.00 | 19.50 | 1255 | 4441 | 0.2825 | 0.5877 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 50.00 | 19.50 | 1354 | 4744 | 0.2853 | 0.5919 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 51.90 | 19.50 | 1417 | 4974 | 0.2848 | 0.5953 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 53.90 | 19.50 | 1514 | 5154 | 0.2944 | 0.6022 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 55.90 | 19.50 | 1584 | 5348 | 0.2975 | 0.6091 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 57.80 | 19.50 | 1654 | 5483 | 0.3038 | 0.6157 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 59.80 | 19.50 | 1735 | 5578 | 0.3130 | 0.6202 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 62.80 | 19.50 | 1795 | 5586 | 0.3234 | 0.6283 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 64.70 | 19.50 | 1853 | 5643 | 0.3308 | 0.6279 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 66.70 | 19.50 | 1925 | 5728 | 0.3380 | 0.6418 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 68.70 | 19.50 | 1962 | 5743 | 0.3436 | 0.6451 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 70.70 | 19.50 | 2084 | 5784 | 0.3614 | 0.6509 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 72.60 | 19.50 | 2182 | 5854 | 0.3733 | 0.6688 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 74.60 | 19.50 | 2221 | 5927 | 0.3753 | 0.6694 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 76.60 | 19.50 | 2327 | 5898 | 0.3947 | 0.6908 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 78.50 | 19.50 | 2393 | 5949 | 0.4023 | 0.6909 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 80.50 | 19.50 | 2455 | 6018 | 0.4079 | 0.6909 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 82.50 | 19.50 | 2559 | 6031 | 0.4242 | 0.6967 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 84.40 | 19.50 | 2655 | 6038 | 0.4397 | 0.7049 |