LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 4.60 | 19.50 | 393 | 295 | 1.3383 | 0.5370 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 6.60 | 19.50 | 451 | 390 | 1.1558 | 0.4653 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 8.60 | 19.50 | 485 | 442 | 1.0983 | 0.5216 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 10.60 | 19.50 | 506 | 467 | 1.0843 | 0.5826 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 12.50 | 19.50 | 527 | 495 | 1.0640 | 0.6536 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 14.50 | 19.50 | 559 | 537 | 1.0396 | 0.6935 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 16.50 | 19.50 | 615 | 626 | 0.9866 | 0.7618 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 18.40 | 19.50 | 731 | 775 | 0.9495 | 0.8069 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 20.40 | 19.50 | 840 | 951 | 0.8971 | 0.8134 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 22.40 | 19.50 | 894 | 1150 | 0.7858 | 0.7805 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 24.30 | 19.50 | 924 | 1322 | 0.6943 | 0.7502 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 26.30 | 19.50 | 926 | 1491 | 0.6183 | 0.7259 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 28.30 | 19.50 | 932 | 1665 | 0.5592 | 0.7136 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 30.30 | 19.50 | 941 | 1887 | 0.4989 | 0.6978 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 32.20 | 19.50 | 949 | 2123 | 0.4476 | 0.6723 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 34.20 | 19.50 | 983 | 2452 | 0.4037 | 0.6566 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 36.20 | 19.50 | 997 | 2641 | 0.3787 | 0.6465 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 38.10 | 19.50 | 1002 | 2867 | 0.3506 | 0.6335 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 40.10 | 19.50 | 1007 | 3104 | 0.3249 | 0.6128 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 42.10 | 19.50 | 1012 | 3461 | 0.2934 | 0.6102 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 44.00 | 19.50 | 1017 | 3824 | 0.2670 | 0.5999 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 46.00 | 19.50 | 1028 | 4146 | 0.2480 | 0.5926 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 48.00 | 19.50 | 1028 | 4441 | 0.2312 | 0.5827 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 50.00 | 19.50 | 1036 | 4744 | 0.2177 | 0.5771 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 51.90 | 19.50 | 1041 | 4974 | 0.2083 | 0.5713 |