LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 68.70 | 19.50 | 6190 | 5743 | 1.0824 | 0.9306 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 70.70 | 19.50 | 6379 | 5784 | 1.1050 | 0.9360 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 72.60 | 19.50 | 6616 | 5854 | 1.1310 | 0.9461 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 74.60 | 19.50 | 6819 | 5927 | 1.1514 | 0.9500 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 76.60 | 19.50 | 7044 | 5898 | 1.1943 | 0.9599 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 78.50 | 19.50 | 7201 | 5949 | 1.2107 | 0.9607 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 80.50 | 19.50 | 7279 | 6018 | 1.2099 | 0.9572 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 82.50 | 19.50 | 7318 | 6031 | 1.2143 | 0.9579 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 84.40 | 19.50 | 7134 | 6038 | 1.1830 | 0.9496 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 86.40 | 19.50 | 7119 | 6081 | 1.1718 | 0.9404 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 88.40 | 19.50 | 6728 | 6064 | 1.1098 | 0.9254 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 90.40 | 19.50 | 6674 | 6097 | 1.0944 | 0.9169 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 92.30 | 19.50 | 6461 | 6153 | 1.0492 | 0.8912 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 94.30 | 19.50 | 6320 | 6154 | 1.0244 | 0.8643 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 2.70 | 19.50 | 215 | 163 | 1.2932 | 0.5520 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 4.60 | 19.50 | 328 | 295 | 1.1038 | 0.4608 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 6.60 | 19.50 | 417 | 390 | 1.0689 | 0.4427 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 8.60 | 19.50 | 463 | 442 | 1.0478 | 0.4839 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 10.60 | 19.50 | 491 | 467 | 1.0502 | 0.5072 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 12.50 | 19.50 | 516 | 495 | 1.0425 | 0.5336 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 14.50 | 19.50 | 566 | 537 | 1.0531 | 0.5562 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 16.50 | 19.50 | 625 | 626 | 0.9995 | 0.5717 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 18.40 | 19.50 | 721 | 775 | 0.9328 | 0.6285 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 20.40 | 19.50 | 807 | 951 | 0.8546 | 0.6160 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 22.40 | 19.50 | 865 | 1150 | 0.7560 | 0.6062 |