LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 53.90 | 19.50 | 1047 | 5154 | 0.2019 | 0.5674 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 55.90 | 19.50 | 1052 | 5348 | 0.1953 | 0.5608 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 57.80 | 19.50 | 1047 | 5483 | 0.1895 | 0.5591 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 59.80 | 19.50 | 1050 | 5578 | 0.1868 | 0.5550 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 62.80 | 19.50 | 1060 | 5586 | 0.1883 | 0.5589 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 64.70 | 19.50 | 1051 | 5643 | 0.1847 | 0.5509 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 66.70 | 19.50 | 1056 | 5728 | 0.1830 | 0.5500 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 68.70 | 19.50 | 1072 | 5743 | 0.1853 | 0.5551 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 70.70 | 19.50 | 1071 | 5784 | 0.1836 | 0.5541 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 72.60 | 19.50 | 1062 | 5854 | 0.1803 | 0.5539 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 74.60 | 19.50 | 1068 | 5927 | 0.1790 | 0.5508 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 76.60 | 19.50 | 1073 | 5898 | 0.1810 | 0.5548 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 78.50 | 19.50 | 1076 | 5949 | 0.1802 | 0.5544 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 80.50 | 19.50 | 1090 | 6018 | 0.1803 | 0.5572 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 82.50 | 19.50 | 1093 | 6031 | 0.1805 | 0.5609 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 84.40 | 19.50 | 1081 | 6038 | 0.1786 | 0.5574 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 86.40 | 19.50 | 1076 | 6081 | 0.1766 | 0.5573 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 88.40 | 19.50 | 1081 | 6064 | 0.1783 | 0.5639 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 90.40 | 19.50 | 1086 | 6097 | 0.1783 | 0.5630 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 92.30 | 19.50 | 1091 | 6153 | 0.1776 | 0.5601 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 94.30 | 19.50 | 1063 | 6154 | 0.1732 | 0.5568 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 2.70 | 19.50 | 210 | 163 | 1.3018 | 0.5945 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 4.60 | 19.50 | 354 | 295 | 1.2057 | 0.5391 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 6.60 | 19.50 | 390 | 390 | 0.9984 | 0.4818 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 8.60 | 19.50 | 390 | 442 | 0.8822 | 0.4786 |