LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 1 | 23.00 | 770.96 | 1405 | 2193 | 0.6427 | 0.4904 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 25.30 | 770.96 | 1392 | 2456 | 0.5684 | 0.4248 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 27.50 | 770.96 | 1398 | 2754 | 0.5094 | 0.3830 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 29.70 | 770.96 | 1392 | 3022 | 0.4622 | 0.3494 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 31.90 | 770.96 | 1401 | 3294 | 0.4266 | 0.3292 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 34.10 | 770.96 | 1396 | 3605 | 0.3884 | 0.3051 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 36.40 | 770.96 | 1411 | 3985 | 0.3552 | 0.2898 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 38.60 | 770.96 | 1394 | 4421 | 0.3163 | 0.2641 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 40.80 | 770.96 | 1400 | 4874 | 0.2882 | 0.2506 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 43.00 | 770.96 | 1414 | 5280 | 0.2685 | 0.2431 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 45.30 | 770.96 | 1409 | 5677 | 0.2489 | 0.2318 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 47.50 | 770.96 | 1423 | 6082 | 0.2346 | 0.2274 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 49.70 | 770.96 | 1421 | 6511 | 0.2186 | 0.2185 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 51.90 | 770.96 | 1440 | 6944 | 0.2077 | 0.2163 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 54.10 | 770.96 | 1446 | 7405 | 0.1958 | 0.2113 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 56.40 | 770.96 | 1452 | 7845 | 0.1855 | 0.2069 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 58.60 | 770.96 | 1443 | 8264 | 0.1751 | 0.1997 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 60.80 | 770.96 | 1436 | 8711 | 0.1653 | 0.1929 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 63.00 | 770.96 | 1443 | 9152 | 0.1580 | 0.1904 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 65.30 | 770.96 | 1441 | 9591 | 0.1505 | 0.1859 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 67.50 | 770.96 | 1451 | 9939 | 0.1462 | 0.1849 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 69.70 | 770.96 | 1442 | 10312 | 0.1400 | 0.1805 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 71.90 | 770.96 | 1445 | 10631 | 0.1361 | 0.1789 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 74.10 | 770.96 | 1450 | 10921 | 0.1329 | 0.1778 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 76.40 | 770.96 | 1464 | 11184 | 0.1311 | 0.1790 |