LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 74.10 | 770.96 | 6286 | 10921 | 0.5755 | 0.7298 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 76.40 | 770.96 | 6537 | 11184 | 0.5844 | 0.7389 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 78.60 | 770.96 | 6811 | 11443 | 0.5951 | 0.7490 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 80.80 | 770.96 | 7057 | 11725 | 0.6018 | 0.7561 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 83.10 | 770.96 | 7358 | 12002 | 0.6130 | 0.7659 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 85.30 | 770.96 | 7660 | 12277 | 0.6239 | 0.7752 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 87.50 | 770.96 | 7919 | 12567 | 0.6302 | 0.7812 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 2.90 | 770.96 | 910 | 886 | 1.0285 | 1.5401 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 5.10 | 770.96 | 861 | 984 | 0.8722 | 0.5393 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 7.30 | 770.96 | 1100 | 1067 | 1.0317 | 1.1690 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 9.60 | 770.96 | 1186 | 1178 | 1.0094 | 1.0594 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 11.90 | 770.96 | 1338 | 1319 | 1.0164 | 1.0558 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 14.10 | 770.96 | 1498 | 1478 | 1.0139 | 1.0327 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 16.40 | 770.96 | 1613 | 1625 | 0.9949 | 0.9947 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 18.60 | 770.96 | 1664 | 1786 | 0.9332 | 0.8919 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 20.80 | 770.96 | 1695 | 1959 | 0.8667 | 0.7994 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 23.00 | 770.96 | 1737 | 2193 | 0.7939 | 0.7162 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 25.30 | 770.96 | 1772 | 2456 | 0.7228 | 0.6467 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 27.50 | 770.96 | 1808 | 2754 | 0.6582 | 0.5920 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 29.70 | 770.96 | 1870 | 3022 | 0.6204 | 0.5686 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 31.90 | 770.96 | 1916 | 3294 | 0.5830 | 0.5448 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 34.10 | 770.96 | 2026 | 3605 | 0.5637 | 0.5445 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 36.40 | 770.96 | 2133 | 3985 | 0.5365 | 0.5364 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 38.60 | 770.96 | 2242 | 4421 | 0.5084 | 0.5279 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 40.80 | 770.96 | 2388 | 4874 | 0.4913 | 0.5297 |