LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 1 | 78.60 | 770.96 | 1469 | 11443 | 0.1285 | 0.1782 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 80.80 | 770.96 | 1459 | 11725 | 0.1245 | 0.1745 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 83.10 | 770.96 | 1449 | 12002 | 0.1208 | 0.1709 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 85.30 | 770.96 | 1463 | 12277 | 0.1192 | 0.1723 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 87.50 | 770.96 | 1454 | 12567 | 0.1157 | 0.1688 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 2.90 | 770.96 | 912 | 886 | 1.0287 | 1.3736 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 5.10 | 770.96 | 1021 | 984 | 1.0370 | 1.2294 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 7.30 | 770.96 | 1097 | 1067 | 1.0271 | 1.1260 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 9.60 | 770.96 | 1203 | 1178 | 1.0204 | 1.0657 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 11.90 | 770.96 | 1339 | 1319 | 1.0140 | 1.0328 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 14.10 | 770.96 | 1518 | 1478 | 1.0260 | 1.0534 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 16.40 | 770.96 | 1667 | 1625 | 1.0247 | 1.0419 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 18.60 | 770.96 | 1818 | 1786 | 1.0159 | 1.0222 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 20.80 | 770.96 | 1975 | 1959 | 1.0071 | 1.0075 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 23.00 | 770.96 | 2162 | 2193 | 0.9849 | 0.9763 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 25.30 | 770.96 | 2462 | 2456 | 1.0009 | 0.9971 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 27.50 | 770.96 | 2756 | 2754 | 0.9993 | 0.9963 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 29.70 | 770.96 | 3044 | 3022 | 1.0057 | 1.0030 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 31.90 | 770.96 | 3343 | 3294 | 1.0136 | 1.0110 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 34.10 | 770.96 | 3586 | 3605 | 0.9935 | 0.9919 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 36.40 | 770.96 | 3957 | 3985 | 0.9917 | 0.9907 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 38.60 | 770.96 | 4381 | 4421 | 0.9897 | 0.9897 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 40.80 | 770.96 | 4857 | 4874 | 0.9954 | 0.9948 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 43.00 | 770.96 | 5338 | 5280 | 1.0103 | 1.0063 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 45.30 | 770.96 | 5695 | 5677 | 1.0027 | 1.0007 |