LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 25.30 | 770.96 | 2402 | 2456 | 0.9778 | 0.9726 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 27.50 | 770.96 | 2656 | 2754 | 0.9643 | 0.9603 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 29.70 | 770.96 | 2869 | 3022 | 0.9494 | 0.9474 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 31.90 | 770.96 | 3093 | 3294 | 0.9393 | 0.9406 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 34.10 | 770.96 | 3309 | 3605 | 0.9184 | 0.9244 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 36.40 | 770.96 | 3578 | 3985 | 0.8982 | 0.9109 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 38.60 | 770.96 | 3891 | 4421 | 0.8804 | 0.9008 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 40.80 | 770.96 | 4257 | 4874 | 0.8736 | 0.9003 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 43.00 | 770.96 | 4616 | 5280 | 0.8747 | 0.9049 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 45.30 | 770.96 | 4880 | 5677 | 0.8599 | 0.8970 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 47.50 | 770.96 | 5137 | 6082 | 0.8447 | 0.8892 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 49.70 | 770.96 | 5450 | 6511 | 0.8375 | 0.8872 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 51.90 | 770.96 | 5800 | 6944 | 0.8354 | 0.8890 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 54.10 | 770.96 | 6191 | 7405 | 0.8362 | 0.8926 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 56.40 | 770.96 | 6520 | 7845 | 0.8313 | 0.8917 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 58.60 | 770.96 | 6853 | 8264 | 0.8297 | 0.8928 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 60.80 | 770.96 | 7229 | 8711 | 0.8304 | 0.8956 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 63.00 | 770.96 | 7610 | 9152 | 0.8318 | 0.8984 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 65.30 | 770.96 | 7915 | 9591 | 0.8255 | 0.8962 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 67.50 | 770.96 | 8232 | 9939 | 0.8286 | 0.8996 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 69.70 | 770.96 | 8564 | 10312 | 0.8307 | 0.9023 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 71.90 | 770.96 | 8937 | 10631 | 0.8408 | 0.9093 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 74.10 | 770.96 | 9178 | 10921 | 0.8405 | 0.9099 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 76.40 | 770.96 | 9489 | 11184 | 0.8486 | 0.9156 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 78.60 | 770.96 | 9837 | 11443 | 0.8598 | 0.9226 |