LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 56.40 | 770.96 | 6871 | 7845 | 0.8757 | 0.9221 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 58.60 | 770.96 | 7299 | 8264 | 0.8831 | 0.9285 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 60.80 | 770.96 | 7690 | 8711 | 0.8826 | 0.9297 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 63.00 | 770.96 | 8122 | 9152 | 0.8873 | 0.9339 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 65.30 | 770.96 | 8531 | 9591 | 0.8892 | 0.9363 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 67.50 | 770.96 | 8921 | 9939 | 0.8973 | 0.9419 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 69.70 | 770.96 | 9230 | 10312 | 0.8948 | 0.9413 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 71.90 | 770.96 | 9536 | 10631 | 0.8967 | 0.9429 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 74.10 | 770.96 | 9817 | 10921 | 0.8987 | 0.9446 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 76.40 | 770.96 | 10081 | 11184 | 0.9011 | 0.9464 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 78.60 | 770.96 | 10389 | 11443 | 0.9077 | 0.9503 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 80.80 | 770.96 | 10665 | 11725 | 0.9094 | 0.9514 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 83.10 | 770.96 | 10962 | 12002 | 0.9132 | 0.9540 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 85.30 | 770.96 | 11248 | 12277 | 0.9162 | 0.9558 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 87.50 | 770.96 | 11531 | 12567 | 0.9176 | 0.9567 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 2.90 | 770.96 | 928 | 886 | 1.0477 | 1.5839 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 5.10 | 770.96 | 1021 | 984 | 1.0374 | 1.2464 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 7.30 | 770.96 | 1103 | 1067 | 1.0339 | 1.1527 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 9.60 | 770.96 | 1213 | 1178 | 1.0294 | 1.1013 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 11.90 | 770.96 | 1388 | 1319 | 1.0522 | 1.1374 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 14.10 | 770.96 | 1585 | 1478 | 1.0718 | 1.1519 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 16.40 | 770.96 | 1736 | 1625 | 1.0685 | 1.1266 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 18.60 | 770.96 | 1828 | 1786 | 1.0229 | 1.0367 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 20.80 | 770.96 | 1992 | 1959 | 1.0168 | 1.0244 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 23.00 | 770.96 | 2170 | 2193 | 0.9896 | 0.9859 |