LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 60.80 | 770.96 | 1751 | 8711 | 0.2012 | 0.2639 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 63.00 | 770.96 | 1748 | 9152 | 0.1910 | 0.2574 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 65.30 | 770.96 | 1778 | 9591 | 0.1854 | 0.2580 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 67.50 | 770.96 | 1809 | 9939 | 0.1821 | 0.2601 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 69.70 | 770.96 | 1836 | 10312 | 0.1781 | 0.2607 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 71.90 | 770.96 | 1849 | 10631 | 0.1739 | 0.2598 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 74.10 | 770.96 | 1867 | 10921 | 0.1710 | 0.2601 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 76.40 | 770.96 | 1897 | 11184 | 0.1696 | 0.2626 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 78.60 | 770.96 | 1924 | 11443 | 0.1682 | 0.2648 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 80.80 | 770.96 | 1945 | 11725 | 0.1659 | 0.2656 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 83.10 | 770.96 | 1968 | 12002 | 0.1640 | 0.2668 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 85.30 | 770.96 | 2001 | 12277 | 0.1630 | 0.2696 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 87.50 | 770.96 | 2058 | 12567 | 0.1638 | 0.2758 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 2.90 | 770.96 | 934 | 886 | 1.0555 | 2.2053 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 5.10 | 770.96 | 1045 | 984 | 1.0639 | 1.5299 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 7.30 | 770.96 | 1131 | 1067 | 1.0606 | 1.3191 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 9.60 | 770.96 | 1230 | 1178 | 1.0457 | 1.1841 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 11.90 | 770.96 | 1339 | 1319 | 1.0164 | 1.0544 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 14.10 | 770.96 | 1460 | 1478 | 0.9880 | 0.9771 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 16.40 | 770.96 | 1539 | 1625 | 0.9486 | 0.9074 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 18.60 | 770.96 | 1565 | 1786 | 0.8782 | 0.7985 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 20.80 | 770.96 | 1592 | 1959 | 0.8143 | 0.7170 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 23.00 | 770.96 | 1585 | 2193 | 0.7242 | 0.6142 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 25.30 | 770.96 | 1574 | 2456 | 0.6423 | 0.5334 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 27.50 | 770.96 | 1569 | 2754 | 0.5710 | 0.4728 |