Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | 2-deoxyglucose | 133 | uM | 12612.177 | 0.9372 | 0.7619 | 0.5119 | |||
| HCC1419 | HER2amp | Luminal | 2-deoxyglucose | 667 | uM | 12612.177 | 0.8087 | 0.3211 | 0.5119 | |||
| HCC1419 | HER2amp | Luminal | 2-deoxyglucose | 3330 | uM | 12612.177 | 0.6941 | -0.0200 | 0.5119 | |||
| HCC1569 | HER2amp | Basal A | 2-deoxyglucose | 0.00853 | uM | 13038.177 | 1.2204 | 1.4856 | 0.9161 | |||
| HCC1569 | HER2amp | Basal A | 2-deoxyglucose | 0.0427 | uM | 13038.177 | 1.1114 | 1.2443 | 0.9161 | |||
| HCC1569 | HER2amp | Basal A | 2-deoxyglucose | 0.213 | uM | 13038.177 | 1.1779 | 1.3913 | 0.9161 | |||
| HCC1569 | HER2amp | Basal A | 2-deoxyglucose | 1.07 | uM | 13038.177 | 1.2163 | 1.4767 | 0.9161 | |||
| HCC1569 | HER2amp | Basal A | 2-deoxyglucose | 5.33 | uM | 13038.177 | 1.2570 | 1.5673 | 0.9161 | |||
| HCC1569 | HER2amp | Basal A | 2-deoxyglucose | 26.7 | uM | 13038.177 | 1.2070 | 1.4559 | 0.9161 | |||
| HCC1569 | HER2amp | Basal A | 2-deoxyglucose | 133 | uM | 13038.177 | 1.0953 | 1.2089 | 0.9161 | |||
| HCC1569 | HER2amp | Basal A | 2-deoxyglucose | 667 | uM | 13038.177 | 0.5864 | 0.1169 | 0.9161 | |||
| HCC1569 | HER2amp | Basal A | 2-deoxyglucose | 3330 | uM | 13038.177 | 0.5053 | -0.0506 | 0.9161 | |||
| HCC1806 | TNBC | Basal A | 2-deoxyglucose | 0.00853 | uM | 12702.177 | 0.9542 | 0.9413 | 1.5730 | |||
| HCC1806 | TNBC | Basal A | 2-deoxyglucose | 0.0427 | uM | 12702.177 | 0.9417 | 0.9250 | 1.5730 | |||
| HCC1806 | TNBC | Basal A | 2-deoxyglucose | 0.213 | uM | 12702.177 | 0.9690 | 0.9604 | 1.5730 | |||
| HCC1806 | TNBC | Basal A | 2-deoxyglucose | 1.07 | uM | 12702.177 | 1.0026 | 1.0033 | 1.5730 | |||
| HCC1806 | TNBC | Basal A | 2-deoxyglucose | 5.33 | uM | 12702.177 | 0.9699 | 0.9616 | 1.5730 | |||
| HCC1806 | TNBC | Basal A | 2-deoxyglucose | 26.7 | uM | 12702.177 | 0.9162 | 0.8918 | 1.5730 | |||
| HCC1806 | TNBC | Basal A | 2-deoxyglucose | 133 | uM | 12702.177 | 0.8986 | 0.8685 | 1.5730 | |||
| HCC1806 | TNBC | Basal A | 2-deoxyglucose | 667 | uM | 12702.177 | 0.6010 | 0.4469 | 1.5730 | |||
| HCC1806 | TNBC | Basal A | 2-deoxyglucose | 3330 | uM | 12702.177 | 0.2822 | -0.1052 | 1.5730 | |||
| HCC38 | TNBC | Basal B | 2-deoxyglucose | 0.00853 | uM | 12617.177 | 0.9731 | 0.9678 | 1.6822 | |||
| HCC38 | TNBC | Basal B | 2-deoxyglucose | 0.0427 | uM | 12617.177 | 0.9554 | 0.9465 | 1.6822 | |||
| HCC38 | TNBC | Basal B | 2-deoxyglucose | 0.213 | uM | 12617.177 | 0.9797 | 0.9758 | 1.6822 | |||
| HCC38 | TNBC | Basal B | 2-deoxyglucose | 1.07 | uM | 12617.177 | 0.9554 | 0.9465 | 1.6822 |