Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-175-VII | HR+ | Luminal | Erlotinib | EGFR | ErbB | 13.3 | uM | 7499.09 | 0.4893 | -0.0775 | 0.9238 | |
| MDA-MB-175-VII | HR+ | Luminal | Erlotinib | EGFR | ErbB | 66.7 | uM | 7499.09 | 0.1822 | -0.6834 | 0.9238 | |
| MDA-MB-175-VII | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7500.091 | 1.1036 | 1.3425 | 0.6237 | |
| MDA-MB-175-VII | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7500.091 | 1.0659 | 1.2156 | 0.6237 | |
| MDA-MB-175-VII | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7500.091 | 0.9228 | 0.7582 | 0.6237 | |
| MDA-MB-175-VII | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7500.091 | 0.9605 | 0.8749 | 0.6237 | |
| MDA-MB-175-VII | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.107 | uM | 7500.091 | 1.0395 | 1.1281 | 0.6237 | |
| MDA-MB-175-VII | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.533 | uM | 7500.091 | 0.8598 | 0.5699 | 0.6237 | |
| MDA-MB-175-VII | HR+ | Luminal | Erlotinib | EGFR | ErbB | 2.67 | uM | 7500.091 | 0.9155 | 0.7360 | 0.6237 | |
| MDA-MB-175-VII | HR+ | Luminal | Erlotinib | EGFR | ErbB | 13.3 | uM | 7500.091 | 0.6112 | -0.0918 | 0.6237 | |
| MDA-MB-175-VII | HR+ | Luminal | Erlotinib | EGFR | ErbB | 66.7 | uM | 7500.091 | 0.2033 | -0.8445 | 0.6237 | |
| MDA-MB-231 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7504.091 | 0.9986 | 0.9986 | 1.9941 | |
| MDA-MB-231 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7504.091 | 0.9211 | 0.9193 | 1.9941 | |
| MDA-MB-231 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7504.091 | 0.9488 | 0.9480 | 1.9941 | |
| MDA-MB-231 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7504.091 | 0.9585 | 0.9579 | 1.9941 | |
| MDA-MB-231 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.107 | uM | 7504.091 | 0.9513 | 0.9505 | 1.9941 | |
| MDA-MB-231 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.533 | uM | 7504.091 | 1.0806 | 1.0793 | 1.9941 | |
| MDA-MB-231 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 2.67 | uM | 7504.091 | 0.8791 | 0.8749 | 1.9941 | |
| MDA-MB-231 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 13.3 | uM | 7504.091 | 0.9218 | 0.9200 | 1.9941 | |
| MDA-MB-231 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 66.7 | uM | 7504.091 | 0.5944 | 0.5407 | 1.9941 | |
| MDA-MB-361 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7505.09 | 1.0360 | 1.1157 | 0.6295 | |
| MDA-MB-361 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7505.09 | 1.0202 | 1.0646 | 0.6295 | |
| MDA-MB-361 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7505.09 | 0.9880 | 0.9619 | 0.6295 | |
| MDA-MB-361 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7505.09 | 0.8947 | 0.6759 | 0.6295 | |
| MDA-MB-361 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.107 | uM | 7505.09 | 0.9809 | 0.9398 | 0.6295 |