Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 9708.002 | 0.3902 | -0.1851 | 1.0482 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 9708.002 | 0.3468 | -0.2719 | 1.0482 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 9708.002 | 0.3990 | -0.1676 | 1.0482 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9723.002 | 1.0688 | 1.1640 | 0.8443 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9723.002 | 1.1520 | 1.3649 | 0.8443 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9723.002 | 1.0792 | 1.1889 | 0.8443 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9723.002 | 1.0036 | 1.0086 | 0.8443 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 9723.002 | 0.6196 | 0.1344 | 0.8443 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 9723.002 | 0.3682 | -0.3875 | 0.8443 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 9723.002 | 0.2822 | -0.5532 | 0.8443 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 9723.002 | 0.4029 | -0.3187 | 0.8443 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 9723.002 | 0.4555 | -0.2119 | 0.8443 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 12964.002 | 1.0368 | 1.1257 | 0.5925 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 12964.002 | 1.0784 | 1.2718 | 0.5925 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 12964.002 | 0.9696 | 0.8986 | 0.5925 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 12964.002 | 0.9060 | 0.6932 | 0.5925 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 12964.002 | 0.6486 | -0.0367 | 0.5925 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 12964.002 | 0.5022 | -0.3746 | 0.5925 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 12964.002 | 0.4352 | -0.5087 | 0.5925 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 12964.002 | 0.3923 | -0.5878 | 0.5925 | |
| MDA-MB-453 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 12964.002 | 0.5137 | -0.3503 | 0.5925 | |
| MDA-MB-468 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 7905.002 | 1.0138 | 1.0665 | 0.4198 | |
| MDA-MB-468 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.000128 | uM | 7905.002 | 1.1414 | 1.7409 | 0.4198 | |
| MDA-MB-468 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.00064 | uM | 7905.002 | 0.9680 | 0.8509 | 0.4198 | |
| MDA-MB-468 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0032 | uM | 7905.002 | 0.7428 | -0.0150 | 0.4198 |