Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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MCF 10A | NM | Basal B | Docetaxel | TUBB | TUBB | 0.000128 | uM | 7867.002 | 1.0709 | 1.0585 | 2.3763 | |
MCF 10A | NM | Basal B | Docetaxel | TUBB | TUBB | 0.00064 | uM | 7867.002 | 0.8798 | 0.8951 | 2.3763 | |
MCF 10A | NM | Basal B | Docetaxel | TUBB | TUBB | 0.0032 | uM | 7867.002 | 0.5054 | 0.5007 | 2.3763 | |
MCF 10A | NM | Basal B | Docetaxel | TUBB | TUBB | 0.016 | uM | 7867.002 | 0.2990 | 0.2033 | 2.3763 | |
MCF 10A | NM | Basal B | Docetaxel | TUBB | TUBB | 0.08 | uM | 7867.002 | 0.2031 | 0.0226 | 2.3763 | |
MCF 10A | NM | Basal B | Docetaxel | TUBB | TUBB | 0.4 | uM | 7867.002 | 0.2044 | 0.0253 | 2.3763 | |
MCF 10A | NM | Basal B | Docetaxel | TUBB | TUBB | 2 | uM | 7867.002 | 0.2417 | 0.1003 | 2.3763 | |
MCF 10A | NM | Basal B | Docetaxel | TUBB | TUBB | 10 | uM | 7867.002 | 0.2309 | 0.0793 | 2.3763 | |
MCF 10A | NM | Basal B | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 7870.002 | 1.0027 | 1.0022 | 2.4447 | |
MCF 10A | NM | Basal B | Docetaxel | TUBB | TUBB | 0.000128 | uM | 7870.002 | 1.0425 | 1.0343 | 2.4447 | |
MCF 10A | NM | Basal B | Docetaxel | TUBB | TUBB | 0.00064 | uM | 7870.002 | 0.8771 | 0.8956 | 2.4447 | |
MCF 10A | NM | Basal B | Docetaxel | TUBB | TUBB | 0.0032 | uM | 7870.002 | 0.4772 | 0.4778 | 2.4447 | |
MCF 10A | NM | Basal B | Docetaxel | TUBB | TUBB | 0.016 | uM | 7870.002 | 0.2983 | 0.2193 | 2.4447 | |
MCF 10A | NM | Basal B | Docetaxel | TUBB | TUBB | 0.08 | uM | 7870.002 | 0.2023 | 0.0403 | 2.4447 | |
MCF 10A | NM | Basal B | Docetaxel | TUBB | TUBB | 0.4 | uM | 7870.002 | 0.1820 | -0.0037 | 2.4447 | |
MCF 10A | NM | Basal B | Docetaxel | TUBB | TUBB | 2 | uM | 7870.002 | 0.2417 | 0.1188 | 2.4447 | |
MCF 10A | NM | Basal B | Docetaxel | TUBB | TUBB | 10 | uM | 7870.002 | 0.2353 | 0.1066 | 2.4447 | |
MCF 10A | NM | Basal B | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9551.002 | 1.0676 | 1.0517 | 2.5642 | |
MCF 10A | NM | Basal B | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9551.002 | 1.1022 | 1.0773 | 2.5642 | |
MCF 10A | NM | Basal B | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9551.002 | 0.9281 | 0.9426 | 2.5642 | |
MCF 10A | NM | Basal B | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9551.002 | 0.4110 | 0.4139 | 2.5642 | |
MCF 10A | NM | Basal B | Docetaxel | TUBB | TUBB | 0.016 | uM | 9551.002 | 0.2352 | 0.1373 | 2.5642 | |
MCF 10A | NM | Basal B | Docetaxel | TUBB | TUBB | 0.08 | uM | 9551.002 | 0.0866 | -0.2296 | 2.5642 | |
MCF 10A | NM | Basal B | Docetaxel | TUBB | TUBB | 0.4 | uM | 9551.002 | 0.0801 | -0.2527 | 2.5642 | |
MCF 10A | NM | Basal B | Docetaxel | TUBB | TUBB | 2 | uM | 9551.002 | 0.1075 | -0.1619 | 2.5642 |