Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47D | HR+ | Luminal | Dactolisib | PI3K | PI3K | 0.267 | uM | 10939.155 | 0.6891 | 0.5642 | 1.5150 | |
| T47D | HR+ | Luminal | Dactolisib | PI3K | PI3K | 1.33 | uM | 10939.155 | 0.3737 | 0.0444 | 1.5150 | |
| T47D | HR+ | Luminal | Dactolisib | PI3K | PI3K | 6.67 | uM | 10939.155 | 0.7204 | 0.6108 | 1.5150 | |
| T47D | HR+ | Luminal | Dactolisib | PI3K | PI3K | 33.3 | uM | 10939.155 | 0.6660 | 0.5293 | 1.5150 | |
| T47DKBLUC | Unknown | Unknown | Dactolisib | PI3K | PI3K | 0.0000853 | uM | 12608.155 | 0.9747 | 0.9562 | 1.1556 | |
| T47DKBLUC | Unknown | Unknown | Dactolisib | PI3K | PI3K | 0.000427 | uM | 12608.155 | 0.9503 | 0.9137 | 1.1556 | |
| T47DKBLUC | Unknown | Unknown | Dactolisib | PI3K | PI3K | 0.00213 | uM | 12608.155 | 0.9394 | 0.8947 | 1.1556 | |
| T47DKBLUC | Unknown | Unknown | Dactolisib | PI3K | PI3K | 0.0107 | uM | 12608.155 | 0.9391 | 0.8942 | 1.1556 | |
| T47DKBLUC | Unknown | Unknown | Dactolisib | PI3K | PI3K | 0.0533 | uM | 12608.155 | 1.0107 | 1.0185 | 1.1556 | |
| T47DKBLUC | Unknown | Unknown | Dactolisib | PI3K | PI3K | 0.267 | uM | 12608.155 | 0.8518 | 0.7408 | 1.1556 | |
| T47DKBLUC | Unknown | Unknown | Dactolisib | PI3K | PI3K | 1.33 | uM | 12608.155 | 0.6281 | 0.3374 | 1.1556 | |
| T47DKBLUC | Unknown | Unknown | Dactolisib | PI3K | PI3K | 6.67 | uM | 12608.155 | 0.7128 | 0.4920 | 1.1556 | |
| T47DKBLUC | Unknown | Unknown | Dactolisib | PI3K | PI3K | 33.3 | uM | 12608.155 | 0.7496 | 0.5585 | 1.1556 | |
| UACC-812 | HER2amp | Luminal | Dactolisib | PI3K | PI3K | 0.0000853 | uM | 10754.146 | 1.0608 | 1.0968 | 1.2483 | |
| UACC-812 | HER2amp | Luminal | Dactolisib | PI3K | PI3K | 0.000427 | uM | 10754.146 | 1.0512 | 1.0816 | 1.2483 | |
| UACC-812 | HER2amp | Luminal | Dactolisib | PI3K | PI3K | 0.00213 | uM | 10754.146 | 1.1069 | 1.1696 | 1.2483 | |
| UACC-812 | HER2amp | Luminal | Dactolisib | PI3K | PI3K | 0.0107 | uM | 10754.146 | 1.0059 | 1.0095 | 1.2483 | |
| UACC-812 | HER2amp | Luminal | Dactolisib | PI3K | PI3K | 0.0533 | uM | 10754.146 | 1.0087 | 1.0139 | 1.2483 | |
| UACC-812 | HER2amp | Luminal | Dactolisib | PI3K | PI3K | 0.267 | uM | 10754.146 | 1.0146 | 1.0234 | 1.2483 | |
| UACC-812 | HER2amp | Luminal | Dactolisib | PI3K | PI3K | 1.33 | uM | 10754.146 | 0.9013 | 0.8402 | 1.2483 | |
| UACC-812 | HER2amp | Luminal | Dactolisib | PI3K | PI3K | 6.67 | uM | 10754.146 | 0.9282 | 0.8842 | 1.2483 | |
| UACC-812 | HER2amp | Luminal | Dactolisib | PI3K | PI3K | 33.3 | uM | 10754.146 | 0.7692 | 0.6208 | 1.2483 | |
| UACC-812 | HER2amp | Luminal | Dactolisib | PI3K | PI3K | 0.0000853 | uM | 11938.155 | 0.9426 | 0.8358 | 0.6903 | |
| UACC-812 | HER2amp | Luminal | Dactolisib | PI3K | PI3K | 0.000427 | uM | 11938.155 | 0.8727 | 0.6418 | 0.6903 | |
| UACC-812 | HER2amp | Luminal | Dactolisib | PI3K | PI3K | 0.00213 | uM | 11938.155 | 0.9440 | 0.8399 | 0.6903 |