Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7864.037 | 0.9587 | 0.9533 | 1.7830 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7864.037 | 1.0224 | 1.0250 | 1.7830 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7864.037 | 0.9706 | 0.9668 | 1.7830 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7864.037 | 0.4934 | 0.3457 | 1.7830 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7864.037 | 0.1812 | -0.2328 | 1.7830 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 4 | uM | 7864.037 | 0.1549 | -0.2972 | 1.7830 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 20 | uM | 7864.037 | 0.1790 | -0.2379 | 1.7830 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 100 | uM | 7864.037 | 0.1183 | -0.3959 | 1.7830 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7864.05 | 1.0878 | 1.1126 | 1.5353 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7864.05 | 0.9709 | 0.9619 | 1.5353 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7864.05 | 1.1046 | 1.1339 | 1.5353 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7864.05 | 0.9731 | 0.9647 | 1.5353 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7864.05 | 0.3570 | 0.0226 | 1.5353 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7864.05 | 0.1535 | -0.4099 | 1.5353 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 4 | uM | 7864.05 | 0.1492 | -0.4208 | 1.5353 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 20 | uM | 7864.05 | 0.2094 | -0.2776 | 1.5353 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 100 | uM | 7864.05 | 0.1042 | -0.5415 | 1.5353 | |
| LY2 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7865.05 | 1.2283 | 1.2935 | 1.5015 | |
| LY2 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7865.05 | 1.0566 | 1.0747 | 1.5015 | |
| LY2 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7865.05 | 1.2889 | 1.3683 | 1.5015 | |
| LY2 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7865.05 | 1.0688 | 1.0906 | 1.5015 | |
| LY2 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7865.05 | 0.4231 | 0.1278 | 1.5015 | |
| LY2 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7865.05 | 0.4178 | 0.1183 | 1.5015 | |
| LY2 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 7865.05 | 0.3884 | 0.0653 | 1.5015 | |
| LY2 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 7865.05 | 0.3593 | 0.0115 | 1.5015 |