Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 1000 | uM | 9878.006 | 0.1408 | -0.5085 | 1.3968 | ||
| SUM52PE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 5000 | uM | 9878.006 | 0.0291 | -0.8412 | 1.3968 | ||
| SUM52PE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 9889.034 | 1.0185 | 1.0268 | 1.3742 | ||
| SUM52PE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.064 | uM | 9889.034 | 0.9829 | 0.9751 | 1.3742 | ||
| SUM52PE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.32 | uM | 9889.034 | 0.9716 | 0.9585 | 1.3742 | ||
| SUM52PE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 1.6 | uM | 9889.034 | 0.7266 | 0.5853 | 1.3742 | ||
| SUM52PE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 8 | uM | 9889.034 | 0.7283 | 0.5880 | 1.3742 | ||
| SUM52PE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 40 | uM | 9889.034 | 0.6995 | 0.5420 | 1.3742 | ||
| SUM52PE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 200 | uM | 9889.034 | 0.6659 | 0.4878 | 1.3742 | ||
| SUM52PE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 1000 | uM | 9889.034 | 0.3832 | -0.0048 | 1.3742 | ||
| SUM52PE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 5000 | uM | 9889.034 | 0.0413 | -0.8034 | 1.3742 | ||
| T47D | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 9033.018 | 0.9865 | 0.9691 | 0.8708 | ||
| T47D | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.064 | uM | 9033.018 | 0.9451 | 0.8743 | 0.8708 | ||
| T47D | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.32 | uM | 9033.018 | 0.8159 | 0.5833 | 0.8708 | ||
| T47D | HR+ | Luminal | CGC-11047 | Polyamine analogue | 1.6 | uM | 9033.018 | 0.7943 | 0.5353 | 0.8708 | ||
| T47D | HR+ | Luminal | CGC-11047 | Polyamine analogue | 8 | uM | 9033.018 | 0.7420 | 0.4197 | 0.8708 | ||
| T47D | HR+ | Luminal | CGC-11047 | Polyamine analogue | 40 | uM | 9033.018 | 0.6919 | 0.3103 | 0.8708 | ||
| T47D | HR+ | Luminal | CGC-11047 | Polyamine analogue | 200 | uM | 9033.018 | 0.5742 | 0.0577 | 0.8708 | ||
| T47D | HR+ | Luminal | CGC-11047 | Polyamine analogue | 1000 | uM | 9033.018 | 0.3000 | -0.4982 | 0.8708 | ||
| T47D | HR+ | Luminal | CGC-11047 | Polyamine analogue | 5000 | uM | 9033.018 | 0.0531 | -0.9313 | 0.8708 | ||
| T47D | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 9897.034 | 1.0438 | 1.2297 | 0.3940 | ||
| T47D | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.064 | uM | 9897.034 | 0.8999 | 0.5303 | 0.3940 | ||
| T47D | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.32 | uM | 9897.034 | 0.7763 | 0.0518 | 0.3940 | ||
| T47D | HR+ | Luminal | CGC-11047 | Polyamine analogue | 1.6 | uM | 9897.034 | 0.7524 | -0.0284 | 0.3940 | ||
| T47D | HR+ | Luminal | CGC-11047 | Polyamine analogue | 8 | uM | 9897.034 | 0.7594 | -0.0052 | 0.3940 |