Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM229PE | TNBC | - | CGC-11047 | Polyamine analogue | 0.0128 | uM | 9860.125 | 0.9979 | 0.9974 | 1.6001 | ||
| SUM229PE | TNBC | - | CGC-11047 | Polyamine analogue | 0.064 | uM | 9860.125 | 1.0098 | 1.0122 | 1.6001 | ||
| SUM229PE | TNBC | - | CGC-11047 | Polyamine analogue | 0.32 | uM | 9860.125 | 0.9178 | 0.8956 | 1.6001 | ||
| SUM229PE | TNBC | - | CGC-11047 | Polyamine analogue | 1.6 | uM | 9860.125 | 0.8954 | 0.8666 | 1.6001 | ||
| SUM229PE | TNBC | - | CGC-11047 | Polyamine analogue | 8 | uM | 9860.125 | 0.8156 | 0.7608 | 1.6001 | ||
| SUM229PE | TNBC | - | CGC-11047 | Polyamine analogue | 40 | uM | 9860.125 | 0.5877 | 0.4346 | 1.6001 | ||
| SUM229PE | TNBC | - | CGC-11047 | Polyamine analogue | 200 | uM | 9860.125 | 0.5385 | 0.3584 | 1.6001 | ||
| SUM229PE | TNBC | - | CGC-11047 | Polyamine analogue | 1000 | uM | 9860.125 | 0.4302 | 0.1805 | 1.6001 | ||
| SUM229PE | TNBC | - | CGC-11047 | Polyamine analogue | 5000 | uM | 9860.125 | 0.0214 | -0.8188 | 1.6001 | ||
| SUM52PE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 7923.018 | 0.6807 | 0.2326 | 0.7947 | ||
| SUM52PE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.064 | uM | 7923.018 | 0.9175 | 0.7945 | 0.7947 | ||
| SUM52PE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.32 | uM | 7923.018 | 0.6699 | 0.2079 | 0.7947 | ||
| SUM52PE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 1.6 | uM | 7923.018 | 0.7044 | 0.2869 | 0.7947 | ||
| SUM52PE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 8 | uM | 7923.018 | 0.6853 | 0.2432 | 0.7947 | ||
| SUM52PE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 40 | uM | 7923.018 | 0.5641 | -0.0270 | 0.7947 | ||
| SUM52PE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 200 | uM | 7923.018 | 0.3588 | -0.4494 | 0.7947 | ||
| SUM52PE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 1000 | uM | 7923.018 | 0.0085 | -0.9950 | 0.7947 | ||
| SUM52PE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 5000 | uM | 7923.018 | 0.0015 | -0.9994 | 0.7947 | ||
| SUM52PE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 9878.006 | 1.0848 | 1.1200 | 1.3968 | ||
| SUM52PE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.064 | uM | 9878.006 | 1.0018 | 1.0025 | 1.3968 | ||
| SUM52PE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.32 | uM | 9878.006 | 0.5265 | 0.2635 | 1.3968 | ||
| SUM52PE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 1.6 | uM | 9878.006 | 0.6230 | 0.4253 | 1.3968 | ||
| SUM52PE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 8 | uM | 9878.006 | 0.6987 | 0.5472 | 1.3968 | ||
| SUM52PE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 40 | uM | 9878.006 | 0.6364 | 0.4472 | 1.3968 | ||
| SUM52PE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 200 | uM | 9878.006 | 0.5300 | 0.2694 | 1.3968 |