Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM185PE | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7921.042 | 1.0331 | 1.1052 | 0.6355 | |
| SUM185PE | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7921.042 | 1.0486 | 1.1551 | 0.6355 | |
| SUM185PE | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7921.042 | 1.0539 | 1.1721 | 0.6355 | |
| SUM185PE | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7921.042 | 1.1091 | 1.3540 | 0.6355 | |
| SUM185PE | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7921.042 | 1.0682 | 1.2188 | 0.6355 | |
| SUM185PE | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7921.042 | 1.0759 | 1.2439 | 0.6355 | |
| SUM185PE | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7921.042 | 1.0502 | 1.1603 | 0.6355 | |
| SUM185PE | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 7921.042 | 1.1105 | 1.3586 | 0.6355 | |
| SUM185PE | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 7921.042 | 1.0126 | 1.0399 | 0.6355 | |
| SUM185PE | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 10146.124 | 1.1455 | 1.3146 | 0.9296 | |
| SUM185PE | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 10146.124 | 1.2111 | 1.4576 | 0.9296 | |
| SUM185PE | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 10146.124 | 1.1348 | 1.2914 | 0.9296 | |
| SUM185PE | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 10146.124 | 1.1060 | 1.2289 | 0.9296 | |
| SUM185PE | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.0011 | uM | 10146.124 | 1.0417 | 1.0899 | 0.9296 | |
| SUM185PE | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 10146.124 | 1.1043 | 1.2252 | 0.9296 | |
| SUM185PE | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.0274 | uM | 10146.124 | 1.0376 | 1.0809 | 0.9296 | |
| SUM185PE | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 10146.124 | 1.1731 | 1.3747 | 0.9296 | |
| SUM185PE | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 10146.124 | 1.0600 | 1.1293 | 0.9296 | |
| SUM229PE | TNBC | - | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 9860.125 | 0.9553 | 0.9437 | 1.6001 | |
| SUM229PE | TNBC | - | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 9860.125 | 0.9252 | 0.9051 | 1.6001 | |
| SUM229PE | TNBC | - | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 9860.125 | 0.9316 | 0.9133 | 1.6001 | |
| SUM229PE | TNBC | - | Cetuximab | EGFR | ErbB | 0.000219 | uM | 9860.125 | 1.0554 | 1.0685 | 1.6001 | |
| SUM229PE | TNBC | - | Cetuximab | EGFR | ErbB | 0.0011 | uM | 9860.125 | 1.0179 | 1.0223 | 1.6001 | |
| SUM229PE | TNBC | - | Cetuximab | EGFR | ErbB | 0.00548 | uM | 9860.125 | 1.0253 | 1.0314 | 1.6001 | |
| SUM229PE | TNBC | - | Cetuximab | EGFR | ErbB | 0.0274 | uM | 9860.125 | 0.9562 | 0.9448 | 1.6001 |