Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Antibody	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MDA-MB-361	HER2amp	Luminal	Cetuximab	EGFR	ErbB	0.0000438	uM	7896.042	0.9968	0.9945	1.1632
MDA-MB-361	HER2amp	Luminal	Cetuximab	EGFR	ErbB	0.000219	uM	7896.042	1.0266	1.0456	1.1632
MDA-MB-361	HER2amp	Luminal	Cetuximab	EGFR	ErbB	0.0011	uM	7896.042	0.9973	0.9953	1.1632
MDA-MB-361	HER2amp	Luminal	Cetuximab	EGFR	ErbB	0.00548	uM	7896.042	1.1054	1.1799	1.1632
MDA-MB-361	HER2amp	Luminal	Cetuximab	EGFR	ErbB	0.0274	uM	7896.042	1.0135	1.0232	1.1632
MDA-MB-361	HER2amp	Luminal	Cetuximab	EGFR	ErbB	0.137	uM	7896.042	1.0530	1.0908	1.1632
MDA-MB-361	HER2amp	Luminal	Cetuximab	EGFR	ErbB	0.685	uM	7896.042	0.9847	0.9737	1.1632
MDA-MB-361	HER2amp	Luminal	Cetuximab	EGFR	ErbB	0.00000175	uM	9648.026	1.0243	1.0691	0.7065
MDA-MB-361	HER2amp	Luminal	Cetuximab	EGFR	ErbB	0.00000877	uM	9648.026	1.0114	1.0323	0.7065
MDA-MB-361	HER2amp	Luminal	Cetuximab	EGFR	ErbB	0.0000438	uM	9648.026	0.9983	0.9951	0.7065
MDA-MB-361	HER2amp	Luminal	Cetuximab	EGFR	ErbB	0.000219	uM	9648.026	0.9997	0.9993	0.7065
MDA-MB-361	HER2amp	Luminal	Cetuximab	EGFR	ErbB	0.0011	uM	9648.026	1.0303	1.0864	0.7065
MDA-MB-361	HER2amp	Luminal	Cetuximab	EGFR	ErbB	0.00548	uM	9648.026	1.0188	1.0533	0.7065
MDA-MB-361	HER2amp	Luminal	Cetuximab	EGFR	ErbB	0.0274	uM	9648.026	1.0393	1.1121	0.7065
MDA-MB-361	HER2amp	Luminal	Cetuximab	EGFR	ErbB	0.137	uM	9648.026	1.0162	1.0461	0.7065
MDA-MB-361	HER2amp	Luminal	Cetuximab	EGFR	ErbB	0.685	uM	9648.026	0.9958	0.9880	0.7065
MDA-MB-415	HR+	Luminal	Cetuximab	EGFR	ErbB	0.00000175	uM	7897.018	0.9752	0.9413	0.8448
MDA-MB-415	HR+	Luminal	Cetuximab	EGFR	ErbB	0.00000877	uM	7897.018	0.9467	0.8745	0.8448
MDA-MB-415	HR+	Luminal	Cetuximab	EGFR	ErbB	0.0000438	uM	7897.018	0.9673	0.9229	0.8448
MDA-MB-415	HR+	Luminal	Cetuximab	EGFR	ErbB	0.000219	uM	7897.018	0.9460	0.8727	0.8448
MDA-MB-415	HR+	Luminal	Cetuximab	EGFR	ErbB	0.0011	uM	7897.018	0.9542	0.8921	0.8448
MDA-MB-415	HR+	Luminal	Cetuximab	EGFR	ErbB	0.00548	uM	7897.018	0.9983	0.9961	0.8448
MDA-MB-415	HR+	Luminal	Cetuximab	EGFR	ErbB	0.0274	uM	7897.018	0.9824	0.9584	0.8448
MDA-MB-415	HR+	Luminal	Cetuximab	EGFR	ErbB	0.137	uM	7897.018	0.9907	0.9779	0.8448
MDA-MB-415	HR+	Luminal	Cetuximab	EGFR	ErbB	0.685	uM	7897.018	0.9410	0.8611	0.8448

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)