Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-175-VII | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 7885.011 | 1.0328 | 1.1306 | 0.5102 | |
| MDA-MB-175-VII | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 7885.011 | 0.9724 | 0.8932 | 0.5102 | |
| MDA-MB-175-VII | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7885.011 | 1.0159 | 1.0627 | 0.5102 | |
| MDA-MB-175-VII | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 7885.011 | 0.9555 | 0.8294 | 0.5102 | |
| MDA-MB-175-VII | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7885.011 | 0.9717 | 0.8907 | 0.5102 | |
| MDA-MB-175-VII | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7885.011 | 0.7955 | 0.2771 | 0.5102 | |
| MDA-MB-175-VII | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7885.011 | 0.2558 | -0.8618 | 0.5102 | |
| MDA-MB-175-VII | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7885.011 | 0.0427 | -0.9959 | 0.5102 | |
| MDA-MB-175-VII | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 7886.011 | 1.0122 | 1.0353 | 0.6942 | |
| MDA-MB-175-VII | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 7886.011 | 1.0180 | 1.0522 | 0.6942 | |
| MDA-MB-175-VII | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 7886.011 | 0.9622 | 0.8919 | 0.6942 | |
| MDA-MB-175-VII | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7886.011 | 1.1260 | 1.3730 | 0.6942 | |
| MDA-MB-175-VII | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 7886.011 | 1.0111 | 1.0320 | 0.6942 | |
| MDA-MB-175-VII | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7886.011 | 0.9721 | 0.9200 | 0.6942 | |
| MDA-MB-175-VII | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7886.011 | 0.6862 | 0.1625 | 0.6942 | |
| MDA-MB-175-VII | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7886.011 | 0.1617 | -0.8551 | 0.6942 | |
| MDA-MB-175-VII | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7886.011 | 0.0142 | -0.9956 | 0.6942 | |
| MDA-MB-231 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 7892.011 | 1.0518 | 1.0390 | 2.6182 | |
| MDA-MB-231 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 7892.011 | 0.9540 | 0.9644 | 2.6182 | |
| MDA-MB-231 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 7892.011 | 0.9817 | 0.9859 | 2.6182 | |
| MDA-MB-231 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7892.011 | 1.0152 | 1.0116 | 2.6182 | |
| MDA-MB-231 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 7892.011 | 0.9754 | 0.9810 | 2.6182 | |
| MDA-MB-231 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7892.011 | 1.0130 | 1.0099 | 2.6182 | |
| MDA-MB-231 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7892.011 | 0.9817 | 0.9859 | 2.6182 | |
| MDA-MB-231 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7892.011 | 0.6196 | 0.6658 | 2.6182 |