Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9028.075 | 1.0316 | 1.1063 | 0.6011 | |
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 2.16 | uM | 9028.075 | 1.0314 | 1.1055 | 0.6011 | |
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9028.075 | 0.8635 | 0.5666 | 0.6011 | |
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9028.075 | 0.4179 | -0.5316 | 0.6011 | |
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9028.075 | 0.1232 | -0.9386 | 0.6011 | |
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9028.075 | 0.1014 | -0.9556 | 0.6011 | |
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9453.011 | 1.4886 | 2.3368 | 0.7773 | |
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9453.011 | 1.5793 | 2.6006 | 0.7773 | |
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9453.011 | 1.4583 | 2.2495 | 0.7773 | |
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9453.011 | 1.5162 | 2.4165 | 0.7773 | |
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 9453.011 | 1.5003 | 2.3705 | 0.7773 | |
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9453.011 | 1.1873 | 1.4945 | 0.7773 | |
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9453.011 | 0.3630 | -0.4569 | 0.7773 | |
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9453.011 | 0.1094 | -0.8839 | 0.7773 | |
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9453.011 | 0.0492 | -0.9585 | 0.7773 | |
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9469.011 | 1.0597 | 1.0991 | 1.1991 | |
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9469.011 | 0.9690 | 0.9481 | 1.1991 | |
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9469.011 | 1.0267 | 1.0444 | 1.1991 | |
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9469.011 | 1.0291 | 1.0485 | 1.1991 | |
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 9469.011 | 1.0090 | 1.0151 | 1.1991 | |
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9469.011 | 0.8403 | 0.7299 | 1.1991 | |
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9469.011 | 0.2392 | -0.3934 | 1.1991 | |
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9469.011 | 0.0703 | -0.7814 | 1.1991 | |
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9469.011 | 0.0267 | -0.9027 | 1.1991 | |
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 10268.12 | 1.5129 | 6.0907 | 0.3272 |