Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HBL-100 | Unknown | Unknown | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7808.05 | 0.9789 | 0.9832 | 2.5177 | |
| HBL-100 | Unknown | Unknown | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7808.05 | 0.9227 | 0.9371 | 2.5177 | |
| HBL-100 | Unknown | Unknown | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7808.05 | 0.9257 | 0.9396 | 2.5177 | |
| HBL-100 | Unknown | Unknown | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7808.05 | 0.8922 | 0.9114 | 2.5177 | |
| HBL-100 | Unknown | Unknown | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7808.05 | 0.5628 | 0.5917 | 2.5177 | |
| HBL-100 | Unknown | Unknown | 17-AAG | HSP90 | HSP90 | 4 | uM | 7808.05 | 0.1099 | -0.1681 | 2.5177 | |
| HBL-100 | Unknown | Unknown | 17-AAG | HSP90 | HSP90 | 20 | uM | 7808.05 | 0.0447 | -0.4181 | 2.5177 | |
| HBL-100 | Unknown | Unknown | 17-AAG | HSP90 | HSP90 | 100 | uM | 7808.05 | 0.0398 | -0.4445 | 2.5177 | |
| HCC1143 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7810.037 | 0.9899 | 0.9803 | 1.0223 | |
| HCC1143 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7810.037 | 1.0436 | 1.0853 | 1.0223 | |
| HCC1143 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7810.037 | 0.9579 | 0.9176 | 1.0223 | |
| HCC1143 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7810.037 | 1.1217 | 1.2378 | 1.0223 | |
| HCC1143 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7810.037 | 0.4689 | -0.0466 | 1.0223 | |
| HCC1143 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7810.037 | 0.4327 | -0.1187 | 1.0223 | |
| HCC1143 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 4 | uM | 7810.037 | 0.4216 | -0.1408 | 1.0223 | |
| HCC1143 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 20 | uM | 7810.037 | 0.3575 | -0.2688 | 1.0223 | |
| HCC1143 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 100 | uM | 7810.037 | 0.1982 | -0.5893 | 1.0223 | |
| HCC1143 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 9233.037 | 1.0137 | 1.0223 | 1.2235 | |
| HCC1143 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 9233.037 | 1.0231 | 1.0376 | 1.2235 | |
| HCC1143 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 9233.037 | 1.0275 | 1.0448 | 1.2235 | |
| HCC1143 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 9233.037 | 1.0771 | 1.1252 | 1.2235 | |
| HCC1143 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 9233.037 | 0.5484 | 0.2240 | 1.2235 | |
| HCC1143 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 9233.037 | 0.3212 | -0.2095 | 1.2235 | |
| HCC1143 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 4 | uM | 9233.037 | 0.3236 | -0.2046 | 1.2235 | |
| HCC1143 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 20 | uM | 9233.037 | 0.3910 | -0.0717 | 1.2235 |