Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1954 | HER2amp | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9386.011 | 0.9434 | 0.9250 | 1.5229 | |
| HCC1954 | HER2amp | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9386.011 | 0.9954 | 0.9940 | 1.5229 | |
| HCC1954 | HER2amp | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9386.011 | 0.9164 | 0.8886 | 1.5229 | |
| HCC1954 | HER2amp | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9386.011 | 0.9662 | 0.9554 | 1.5229 | |
| HCC1954 | HER2amp | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 9386.011 | 0.9202 | 0.8937 | 1.5229 | |
| HCC1954 | HER2amp | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9386.011 | 0.9150 | 0.8866 | 1.5229 | |
| HCC1954 | HER2amp | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9386.011 | 0.5943 | 0.4211 | 1.5229 | |
| HCC1954 | HER2amp | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9386.011 | 0.0962 | -0.5702 | 1.5229 | |
| HCC1954 | HER2amp | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9386.011 | 0.0640 | -0.6710 | 1.5229 | |
| HCC202 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 7841.075 | 0.9916 | 0.9690 | 0.5408 | |
| HCC202 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 7841.075 | 0.9213 | 0.7188 | 0.5408 | |
| HCC202 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 7841.075 | 0.9735 | 0.9029 | 0.5408 | |
| HCC202 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7841.075 | 1.0287 | 1.1075 | 0.5408 | |
| HCC202 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.16 | uM | 7841.075 | 0.9920 | 0.9706 | 0.5408 | |
| HCC202 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7841.075 | 1.0390 | 1.1465 | 0.5408 | |
| HCC202 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7841.075 | 0.7336 | 0.1280 | 0.5408 | |
| HCC202 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7841.075 | 0.1558 | -0.9357 | 0.5408 | |
| HCC202 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7841.075 | 0.0346 | -0.9960 | 0.5408 | |
| HCC202 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9402.011 | 1.0436 | 1.2681 | 0.3388 | |
| HCC202 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9402.011 | 1.0197 | 1.1183 | 0.3388 | |
| HCC202 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9402.011 | 0.9819 | 0.8951 | 0.3388 | |
| HCC202 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9402.011 | 1.0462 | 1.2852 | 0.3388 | |
| HCC202 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 9402.011 | 1.1354 | 1.9090 | 0.3388 | |
| HCC202 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9402.011 | 0.9107 | 0.5176 | 0.3388 | |
| HCC202 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9402.011 | 0.6776 | -0.3658 | 0.3388 |