Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7541.074 | 0.9995 | 0.9992 | 1.3223 | |
| SUM52PE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7541.074 | 0.9653 | 0.9473 | 1.3223 | |
| SUM52PE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7541.074 | 0.9653 | 0.9473 | 1.3223 | |
| SUM52PE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7541.074 | 0.2675 | -0.2622 | 1.3223 | |
| SUM52PE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7541.074 | 0.2675 | -0.2622 | 1.3223 | |
| SUM52PE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7541.074 | 0.1899 | -0.4305 | 1.3223 | |
| SUM52PE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7541.074 | 0.1899 | -0.4305 | 1.3223 | |
| SUM52PE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7541.074 | 0.1440 | -0.5380 | 1.3223 | |
| SUM52PE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7541.074 | 0.1440 | -0.5380 | 1.3223 | |
| SUM52PE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7541.074 | 0.1265 | -0.5811 | 1.3223 | |
| SUM52PE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7541.074 | 0.1265 | -0.5811 | 1.3223 | |
| SUM52PE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7541.074 | 0.1312 | -0.5695 | 1.3223 | |
| SUM52PE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7541.074 | 0.1312 | -0.5695 | 1.3223 | |
| SUM52PE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7541.074 | 0.1503 | -0.5228 | 1.3223 | |
| SUM52PE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7541.074 | 0.1503 | -0.5228 | 1.3223 | |
| SUM52PE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14811.203 | 1.1567 | 1.3099 | 1.0107 | |
| SUM52PE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14811.203 | 1.1567 | 1.3099 | 1.0107 | |
| SUM52PE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14811.203 | 0.9694 | 0.9395 | 1.0107 | |
| SUM52PE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14811.203 | 0.9694 | 0.9395 | 1.0107 | |
| SUM52PE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14811.203 | 0.6435 | 0.2931 | 1.0107 | |
| SUM52PE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14811.203 | 0.6435 | 0.2931 | 1.0107 | |
| SUM52PE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14811.203 | 0.5539 | 0.1148 | 1.0107 | |
| SUM52PE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14811.203 | 0.5539 | 0.1148 | 1.0107 | |
| SUM52PE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14811.203 | 0.4449 | -0.1025 | 1.0107 | |
| SUM52PE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14811.203 | 0.4449 | -0.1025 | 1.0107 |