Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14921.203 | 0.9499 | 0.9669 | 3.0799 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14921.203 | 0.7099 | 0.7894 | 3.0799 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14921.203 | 0.7099 | 0.7894 | 3.0799 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14921.203 | 0.0883 | -0.0906 | 3.0799 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14921.203 | 0.0883 | -0.0906 | 3.0799 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14921.203 | 0.0021 | -0.7306 | 3.0799 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14921.203 | 0.0021 | -0.7306 | 3.0799 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14921.203 | 0.0028 | -0.7042 | 3.0799 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14921.203 | 0.0028 | -0.7042 | 3.0799 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14921.203 | 0.0017 | -0.7494 | 3.0799 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14921.203 | 0.0017 | -0.7494 | 3.0799 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14921.203 | 0.0019 | -0.7366 | 3.0799 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14921.203 | 0.0019 | -0.7366 | 3.0799 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14921.203 | 0.0025 | -0.7142 | 3.0799 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14921.203 | 0.0025 | -0.7142 | 3.0799 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14921.203 | 0.0042 | -0.6626 | 3.0799 | |
| SUM159PT | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14921.203 | 0.0042 | -0.6626 | 3.0799 | |
| SUM185PE | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7532.074 | 1.0665 | 1.1737 | 0.7728 | |
| SUM185PE | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7532.074 | 1.0665 | 1.1737 | 0.7728 | |
| SUM185PE | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7532.074 | 1.0129 | 1.0336 | 0.7728 | |
| SUM185PE | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7532.074 | 1.0129 | 1.0336 | 0.7728 | |
| SUM185PE | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7532.074 | 1.0324 | 1.0842 | 0.7728 | |
| SUM185PE | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7532.074 | 1.0324 | 1.0842 | 0.7728 | |
| SUM185PE | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7532.074 | 0.5936 | 0.0184 | 0.7728 | |
| SUM185PE | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7532.074 | 0.5936 | 0.0184 | 0.7728 |