Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7472.074 | 0.0749 | -0.6072 | 1.5922 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7472.074 | 0.0447 | -0.7160 | 1.5922 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7472.074 | 0.0447 | -0.7160 | 1.5922 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7472.074 | 0.0436 | -0.7205 | 1.5922 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7472.074 | 0.0436 | -0.7205 | 1.5922 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7472.074 | 0.0601 | -0.6581 | 1.5922 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7472.074 | 0.0601 | -0.6581 | 1.5922 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 167 | uM | 7472.074 | 0.0545 | -0.6783 | 1.5922 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 167 | uM | 7472.074 | 0.0545 | -0.6783 | 1.5922 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7473.074 | 0.9605 | 0.9685 | 2.5364 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7473.074 | 0.9605 | 0.9685 | 2.5364 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7473.074 | 1.1685 | 1.1266 | 2.5364 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7473.074 | 1.1685 | 1.1266 | 2.5364 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7473.074 | 1.1708 | 1.1283 | 2.5364 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7473.074 | 1.1708 | 1.1283 | 2.5364 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7473.074 | 1.0220 | 1.0173 | 2.5364 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7473.074 | 1.0220 | 1.0173 | 2.5364 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7473.074 | 0.0470 | -0.4010 | 2.5364 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7473.074 | 0.0470 | -0.4010 | 2.5364 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7473.074 | 0.0344 | -0.4702 | 2.5364 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7473.074 | 0.0344 | -0.4702 | 2.5364 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7473.074 | 0.0107 | -0.6652 | 2.5364 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7473.074 | 0.0107 | -0.6652 | 2.5364 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7473.074 | 0.0146 | -0.6225 | 2.5364 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7473.074 | 0.0146 | -0.6225 | 2.5364 |