Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7466.074 | 0.9792 | 0.9573 | 0.9724 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7466.074 | 0.9680 | 0.9342 | 0.9724 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7466.074 | 0.9680 | 0.9342 | 0.9724 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7466.074 | 0.7945 | 0.5786 | 0.9724 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7466.074 | 0.7945 | 0.5786 | 0.9724 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7466.074 | 0.0193 | -0.9655 | 0.9724 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7466.074 | 0.0193 | -0.9655 | 0.9724 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7466.074 | 0.0112 | -0.9803 | 0.9724 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7466.074 | 0.0112 | -0.9803 | 0.9724 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7466.074 | 0.0073 | -0.9873 | 0.9724 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7466.074 | 0.0073 | -0.9873 | 0.9724 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7466.074 | 0.0102 | -0.9821 | 0.9724 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7466.074 | 0.0102 | -0.9821 | 0.9724 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 167 | uM | 7466.074 | 0.0096 | -0.9831 | 0.9724 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 167 | uM | 7466.074 | 0.0096 | -0.9831 | 0.9724 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7467.074 | 1.0037 | 1.0060 | 1.2457 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7467.074 | 1.0037 | 1.0060 | 1.2457 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7467.074 | 0.9969 | 0.9951 | 1.2457 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7467.074 | 0.9969 | 0.9951 | 1.2457 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7467.074 | 1.0004 | 1.0007 | 1.2457 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7467.074 | 1.0004 | 1.0007 | 1.2457 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7467.074 | 0.8178 | 0.7018 | 1.2457 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7467.074 | 0.8178 | 0.7018 | 1.2457 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7467.074 | 0.0864 | -0.7199 | 1.2457 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7467.074 | 0.0864 | -0.7199 | 1.2457 |