Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC202 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7458.074 | 1.0576 | 1.2900 | 0.4138 | |
| HCC202 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7458.074 | 1.0576 | 1.2900 | 0.4138 | |
| HCC202 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7458.074 | 1.0290 | 1.1430 | 0.4138 | |
| HCC202 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7458.074 | 1.0290 | 1.1430 | 0.4138 | |
| HCC202 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7458.074 | 1.0317 | 1.1569 | 0.4138 | |
| HCC202 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7458.074 | 1.0317 | 1.1569 | 0.4138 | |
| HCC202 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7458.074 | 0.1910 | -0.9634 | 0.4138 | |
| HCC202 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7458.074 | 0.1910 | -0.9634 | 0.4138 | |
| HCC202 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7458.074 | 0.0517 | -0.9984 | 0.4138 | |
| HCC202 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7458.074 | 0.0517 | -0.9984 | 0.4138 | |
| HCC202 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7458.074 | 0.0257 | -0.9997 | 0.4138 | |
| HCC202 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7458.074 | 0.0257 | -0.9997 | 0.4138 | |
| HCC202 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7458.074 | 0.0156 | -0.9999 | 0.4138 | |
| HCC202 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7458.074 | 0.0156 | -0.9999 | 0.4138 | |
| HCC202 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7458.074 | 0.0170 | -0.9999 | 0.4138 | |
| HCC202 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7458.074 | 0.0170 | -0.9999 | 0.4138 | |
| HCC202 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7458.074 | 0.0181 | -0.9999 | 0.4138 | |
| HCC202 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7458.074 | 0.0181 | -0.9999 | 0.4138 | |
| HCC2185 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7462.074 | 0.9945 | 0.9821 | 0.6126 | |
| HCC2185 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7462.074 | 0.9945 | 0.9821 | 0.6126 | |
| HCC2185 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7462.074 | 0.9575 | 0.8630 | 0.6126 | |
| HCC2185 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7462.074 | 0.9575 | 0.8630 | 0.6126 | |
| HCC2185 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7462.074 | 0.7142 | 0.1547 | 0.6126 | |
| HCC2185 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7462.074 | 0.7142 | 0.1547 | 0.6126 | |
| HCC2185 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7462.074 | 0.6479 | -0.0153 | 0.6126 |