Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1954 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7456.074 | 0.9891 | 0.9889 | 1.9647 | |
| HCC1954 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7456.074 | 0.9891 | 0.9889 | 1.9647 | |
| HCC1954 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7456.074 | 0.5227 | 0.4376 | 1.9647 | |
| HCC1954 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7456.074 | 0.5227 | 0.4376 | 1.9647 | |
| HCC1954 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7456.074 | 0.0491 | -0.5685 | 1.9647 | |
| HCC1954 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7456.074 | 0.0491 | -0.5685 | 1.9647 | |
| HCC1954 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7456.074 | 0.0446 | -0.5893 | 1.9647 | |
| HCC1954 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7456.074 | 0.0446 | -0.5893 | 1.9647 | |
| HCC1954 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7456.074 | 0.0225 | -0.7100 | 1.9647 | |
| HCC1954 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7456.074 | 0.0225 | -0.7100 | 1.9647 | |
| HCC1954 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7456.074 | 0.0261 | -0.6875 | 1.9647 | |
| HCC1954 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7456.074 | 0.0261 | -0.6875 | 1.9647 | |
| HCC1954 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 167 | uM | 7456.074 | 0.0342 | -0.6412 | 1.9647 | |
| HCC1954 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 167 | uM | 7456.074 | 0.0342 | -0.6412 | 1.9647 | |
| HCC1954 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7457.074 | 0.9307 | 0.9148 | 1.6514 | |
| HCC1954 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7457.074 | 0.9307 | 0.9148 | 1.6514 | |
| HCC1954 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7457.074 | 0.9830 | 0.9793 | 1.6514 | |
| HCC1954 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7457.074 | 0.9830 | 0.9793 | 1.6514 | |
| HCC1954 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7457.074 | 0.8826 | 0.8543 | 1.6514 | |
| HCC1954 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7457.074 | 0.8826 | 0.8543 | 1.6514 | |
| HCC1954 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7457.074 | 0.3289 | 0.0200 | 1.6514 | |
| HCC1954 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7457.074 | 0.3289 | 0.0200 | 1.6514 | |
| HCC1954 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7457.074 | 0.0152 | -0.8413 | 1.6514 | |
| HCC1954 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7457.074 | 0.0152 | -0.8413 | 1.6514 | |
| HCC1954 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7457.074 | 0.0343 | -0.7406 | 1.6514 |