Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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184A1 | NM | Basal | Bortezomib | Proteasome | Proteasome | 167 | uM | 5894.074 | 0.0861 | -0.6297 | 1.4541 | |
184A1 | NM | Basal | Bortezomib | Proteasome | Proteasome | 167 | uM | 5894.074 | 0.0861 | -0.6297 | 1.4541 | |
184A1 | NM | Basal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 5895.074 | 1.0527 | 1.0937 | 1.1218 | |
184A1 | NM | Basal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 5895.074 | 1.0527 | 1.0937 | 1.1218 | |
184A1 | NM | Basal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 5895.074 | 1.0182 | 1.0324 | 1.1218 | |
184A1 | NM | Basal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 5895.074 | 1.0182 | 1.0324 | 1.1218 | |
184A1 | NM | Basal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 5895.074 | 0.8358 | 0.7045 | 1.1218 | |
184A1 | NM | Basal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 5895.074 | 0.8358 | 0.7045 | 1.1218 | |
184A1 | NM | Basal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 5895.074 | 0.4413 | -0.0354 | 1.1218 | |
184A1 | NM | Basal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 5895.074 | 0.4413 | -0.0354 | 1.1218 | |
184A1 | NM | Basal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 5895.074 | 0.4505 | -0.0175 | 1.1218 | |
184A1 | NM | Basal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 5895.074 | 0.4505 | -0.0175 | 1.1218 | |
184A1 | NM | Basal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 5895.074 | 0.3035 | -0.3091 | 1.1218 | |
184A1 | NM | Basal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 5895.074 | 0.3035 | -0.3091 | 1.1218 | |
184A1 | NM | Basal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 5895.074 | 0.0915 | -0.7627 | 1.1218 | |
184A1 | NM | Basal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 5895.074 | 0.0915 | -0.7627 | 1.1218 | |
184A1 | NM | Basal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 5895.074 | 0.0612 | -0.8342 | 1.1218 | |
184A1 | NM | Basal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 5895.074 | 0.0612 | -0.8342 | 1.1218 | |
184A1 | NM | Basal | Bortezomib | Proteasome | Proteasome | 167 | uM | 5895.074 | 0.0864 | -0.7745 | 1.1218 | |
184A1 | NM | Basal | Bortezomib | Proteasome | Proteasome | 167 | uM | 5895.074 | 0.0864 | -0.7745 | 1.1218 | |
184B5 | NM | Basal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 5896.074 | 1.0197 | 1.0278 | 1.4124 | |
184B5 | NM | Basal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 5896.074 | 1.0197 | 1.0278 | 1.4124 | |
184B5 | NM | Basal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 5896.074 | 0.9659 | 0.9514 | 1.4124 | |
184B5 | NM | Basal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 5896.074 | 0.9659 | 0.9514 | 1.4124 | |
184B5 | NM | Basal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 5896.074 | 0.7835 | 0.6826 | 1.4124 |