Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14116.189 | 0.0088 | -0.9997 | 0.5416 | |
| BT-20 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14230.189 | 0.9922 | 0.9665 | 0.4635 | |
| BT-20 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14230.189 | 0.9762 | 0.8987 | 0.4635 | |
| BT-20 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14230.189 | 1.0039 | 1.0167 | 0.4635 | |
| BT-20 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14230.189 | 0.9889 | 0.9522 | 0.4635 | |
| BT-20 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14230.189 | 0.9685 | 0.8667 | 0.4635 | |
| BT-20 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14230.189 | 0.6906 | -0.1001 | 0.4635 | |
| BT-20 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14230.189 | 0.0093 | -0.9999 | 0.4635 | |
| BT-20 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14230.189 | 0.0087 | -0.9999 | 0.4635 | |
| BT-20 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14230.189 | 0.0067 | -1.0000 | 0.4635 | |
| BT-474 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14119.189 | 1.0069 | 1.0113 | 1.2143 | |
| BT-474 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14119.189 | 0.9732 | 0.9558 | 1.2143 | |
| BT-474 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14119.189 | 0.9725 | 0.9546 | 1.2143 | |
| BT-474 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14119.189 | 0.9546 | 0.9249 | 1.2143 | |
| BT-474 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14119.189 | 0.9998 | 0.9996 | 1.2143 | |
| BT-474 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14119.189 | 0.9430 | 0.9056 | 1.2143 | |
| BT-474 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14119.189 | 0.4626 | 0.0600 | 1.2143 | |
| BT-474 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14119.189 | 0.2075 | -0.4523 | 1.2143 | |
| BT-474 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14119.189 | 0.1675 | -0.5407 | 1.2143 | |
| BT-474 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14233.189 | 0.9809 | 0.9004 | 0.3780 | |
| BT-474 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14233.189 | 0.9737 | 0.8638 | 0.3780 | |
| BT-474 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14233.189 | 1.0151 | 1.0808 | 0.3780 | |
| BT-474 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14233.189 | 0.9826 | 0.9093 | 0.3780 | |
| BT-474 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14233.189 | 0.9682 | 0.8362 | 0.3780 | |
| BT-474 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14233.189 | 0.7716 | 0.0072 | 0.3780 |