Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AU565 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14113.189 | 0.9167 | 0.8847 | 1.4645 | |
| AU565 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14113.189 | 0.9716 | 0.9611 | 1.4645 | |
| AU565 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14113.189 | 0.9544 | 0.9373 | 1.4645 | |
| AU565 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14113.189 | 1.0103 | 1.0141 | 1.4645 | |
| AU565 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14113.189 | 0.8684 | 0.8163 | 1.4645 | |
| AU565 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14113.189 | 0.0173 | -0.8745 | 1.4645 | |
| AU565 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14113.189 | 0.0196 | -0.8637 | 1.4645 | |
| AU565 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14113.189 | 0.0205 | -0.8595 | 1.4645 | |
| AU565 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14613.189 | 0.9635 | 0.9535 | 1.5791 | |
| AU565 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14613.189 | 0.9608 | 0.9500 | 1.5791 | |
| AU565 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14613.189 | 0.9691 | 0.9606 | 1.5791 | |
| AU565 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14613.189 | 0.9201 | 0.8973 | 1.5791 | |
| AU565 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14613.189 | 0.9490 | 0.9348 | 1.5791 | |
| AU565 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14613.189 | 0.2554 | -0.1574 | 1.5791 | |
| AU565 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14613.189 | 0.0138 | -0.8671 | 1.5791 | |
| AU565 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14613.189 | 0.0193 | -0.8356 | 1.5791 | |
| AU565 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14613.189 | 0.0383 | -0.7464 | 1.5791 | |
| BT-20 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14116.189 | 0.8786 | 0.5748 | 0.5416 | |
| BT-20 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14116.189 | 0.8610 | 0.5172 | 0.5416 | |
| BT-20 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14116.189 | 0.8396 | 0.4481 | 0.5416 | |
| BT-20 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14116.189 | 0.7758 | 0.2515 | 0.5416 | |
| BT-20 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14116.189 | 0.8891 | 0.6098 | 0.5416 | |
| BT-20 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14116.189 | 0.0808 | -0.9808 | 0.5416 | |
| BT-20 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14116.189 | 0.0079 | -0.9997 | 0.5416 | |
| BT-20 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14116.189 | 0.0148 | -0.9992 | 0.5416 |