Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1187 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 0.24 | uM | 7432.065 | 1.1355 | 1.3451 | 0.7981 | |
| HCC1187 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 1.2 | uM | 7432.065 | 1.1906 | 1.4887 | 0.7981 | |
| HCC1187 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 6 | uM | 7432.065 | 1.0289 | 1.0727 | 0.7981 | |
| HCC1187 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 30 | uM | 7432.065 | 0.3743 | -0.4161 | 0.7981 | |
| HCC1187 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 150 | uM | 7432.065 | 0.1392 | -0.8309 | 0.7981 | |
| HCC1187 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 750 | uM | 7432.065 | 0.0160 | -0.9887 | 0.7981 | |
| HCC1187 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 3750 | uM | 7432.065 | 0.0109 | -0.9931 | 0.7981 | |
| HCC1187 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 18700 | uM | 7432.065 | 0.0121 | -0.9921 | 0.7981 | |
| HCC1187 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 0.048 | uM | 7433.065 | 0.9846 | 0.9651 | 0.8820 | |
| HCC1187 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 0.24 | uM | 7433.065 | 1.0673 | 1.1533 | 0.8820 | |
| HCC1187 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 1.2 | uM | 7433.065 | 1.0100 | 1.0226 | 0.8820 | |
| HCC1187 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 6 | uM | 7433.065 | 0.9527 | 0.8932 | 0.8820 | |
| HCC1187 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 30 | uM | 7433.065 | 0.5329 | -0.0203 | 0.8820 | |
| HCC1187 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 150 | uM | 7433.065 | 0.1682 | -0.7349 | 0.8820 | |
| HCC1187 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 750 | uM | 7433.065 | 0.0175 | -0.9797 | 0.8820 | |
| HCC1187 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 3750 | uM | 7433.065 | 0.0161 | -0.9815 | 0.8820 | |
| HCC1187 | TNBC | Basal A | Vorinostat | HDAC | HDAC | 18700 | uM | 7433.065 | 0.0128 | -0.9857 | 0.8820 | |
| HCC1395 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 0.048 | uM | 7435.065 | 0.9179 | 0.8085 | 0.8513 | |
| HCC1395 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 0.24 | uM | 7435.065 | 0.9438 | 0.8685 | 0.8513 | |
| HCC1395 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 1.2 | uM | 7435.065 | 0.9431 | 0.8670 | 0.8513 | |
| HCC1395 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 6 | uM | 7435.065 | 1.0392 | 1.0925 | 0.8513 | |
| HCC1395 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 30 | uM | 7435.065 | 1.0658 | 1.1554 | 0.8513 | |
| HCC1395 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 150 | uM | 7435.065 | 0.8545 | 0.6626 | 0.8513 | |
| HCC1395 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 750 | uM | 7435.065 | 0.4985 | -0.1173 | 0.8513 | |
| HCC1395 | TNBC | Basal B | Vorinostat | HDAC | HDAC | 3750 | uM | 7435.065 | 0.1665 | -0.7566 | 0.8513 |