Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7923.018 | 0.5868 | 0.0226 | 0.7947 | |
| SUM52PE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7923.018 | 0.6559 | 0.1764 | 0.7947 | |
| SUM52PE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7923.018 | 0.6616 | 0.1892 | 0.7947 | |
| SUM52PE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7923.018 | 0.7947 | 0.4977 | 0.7947 | |
| SUM52PE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7923.018 | 0.5249 | -0.1113 | 0.7947 | |
| SUM52PE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7923.018 | 0.0838 | -0.9116 | 0.7947 | |
| SUM52PE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.00119 | uM | 9878.006 | 1.0150 | 1.0214 | 1.3968 | |
| SUM52PE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.00593 | uM | 9878.006 | 0.8797 | 0.8247 | 1.3968 | |
| SUM52PE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.0297 | uM | 9878.006 | 0.2422 | -0.2754 | 1.3968 | |
| SUM52PE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.148 | uM | 9878.006 | 0.2957 | -0.1641 | 1.3968 | |
| SUM52PE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.742 | uM | 9878.006 | 0.3361 | -0.0837 | 1.3968 | |
| SUM52PE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 3.71 | uM | 9878.006 | 0.3567 | -0.0438 | 1.3968 | |
| SUM52PE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 18.5 | uM | 9878.006 | 0.2700 | -0.2167 | 1.3968 | |
| SUM52PE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 92.7 | uM | 9878.006 | 0.0242 | -0.8608 | 1.3968 | |
| SUM52PE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 463 | uM | 9878.006 | 0.0101 | -0.9257 | 1.3968 | |
| T47D | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 9033.018 | 0.9741 | 0.9407 | 0.8708 | |
| T47D | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 9033.018 | 1.0318 | 1.0733 | 0.8708 | |
| T47D | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 9033.018 | 1.0239 | 1.0549 | 0.8708 | |
| T47D | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 9033.018 | 0.6416 | 0.2014 | 0.8708 | |
| T47D | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 9033.018 | 0.7977 | 0.5427 | 0.8708 | |
| T47D | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.371 | uM | 9033.018 | 0.8730 | 0.7111 | 0.8708 | |
| T47D | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 1.85 | uM | 9033.018 | 0.8384 | 0.6335 | 0.8708 | |
| T47D | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 9033.018 | 0.6179 | 0.1505 | 0.8708 | |
| T47D | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 46.4 | uM | 9033.018 | 0.0119 | -0.9876 | 0.8708 | |
| UACC-812 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7926.018 | 0.9909 | 0.9826 | 1.0502 |