Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-175-VII | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10818.072 | 0.6649 | -0.2313 | 0.4268 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7506.073 | 1.0935 | 1.1878 | 0.9958 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7506.073 | 1.0014 | 1.0028 | 0.9958 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7506.073 | 0.9778 | 0.9555 | 0.9958 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7506.073 | 1.0463 | 1.0930 | 0.9958 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7506.073 | 0.9970 | 0.9940 | 0.9958 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7506.073 | 1.0478 | 1.0960 | 0.9958 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7506.073 | 1.0117 | 1.0234 | 0.9958 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7506.073 | 1.0850 | 1.1708 | 0.9958 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7506.073 | 0.8671 | 0.7332 | 0.9958 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10472.072 | 0.9872 | 0.9585 | 0.6135 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10472.072 | 1.0109 | 1.0357 | 0.6135 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10472.072 | 0.9850 | 0.9513 | 0.6135 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10472.072 | 1.0307 | 1.1012 | 0.6135 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10472.072 | 1.0552 | 1.1832 | 0.6135 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10472.072 | 0.9819 | 0.9415 | 0.6135 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10472.072 | 1.0034 | 1.0111 | 0.6135 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10472.072 | 0.9712 | 0.9068 | 0.6135 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10472.072 | 0.8744 | 0.6069 | 0.6135 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10643.072 | 1.0501 | 1.1662 | 0.6128 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10643.072 | 1.0046 | 1.0149 | 0.6128 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10643.072 | 1.0255 | 1.0838 | 0.6128 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10643.072 | 1.0617 | 1.2051 | 0.6128 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10643.072 | 1.0268 | 1.0883 | 0.6128 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10643.072 | 1.0043 | 1.0142 | 0.6128 |