Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | Triciribine | AKT | AKT | 0.267 | uM | 7462.074 | 0.7479 | 0.2449 | 0.6126 | |
| HCC2185 | TNBC | Luminal | Triciribine | AKT | AKT | 1.33 | uM | 7462.074 | 0.4516 | -0.4536 | 0.6126 | |
| HCC2185 | TNBC | Luminal | Triciribine | AKT | AKT | 6.67 | uM | 7462.074 | 0.5942 | -0.1449 | 0.6126 | |
| HCC2185 | TNBC | Luminal | Triciribine | AKT | AKT | 33.3 | uM | 7462.074 | 0.5539 | -0.2375 | 0.6126 | |
| HCC2185 | TNBC | Luminal | Triciribine | AKT | AKT | 0.0000853 | uM | 7463.074 | 0.9783 | 0.9064 | 0.4574 | |
| HCC2185 | TNBC | Luminal | Triciribine | AKT | AKT | 0.000427 | uM | 7463.074 | 0.9691 | 0.8675 | 0.4574 | |
| HCC2185 | TNBC | Luminal | Triciribine | AKT | AKT | 0.00213 | uM | 7463.074 | 0.9225 | 0.6765 | 0.4574 | |
| HCC2185 | TNBC | Luminal | Triciribine | AKT | AKT | 0.0107 | uM | 7463.074 | 0.8255 | 0.3152 | 0.4574 | |
| HCC2185 | TNBC | Luminal | Triciribine | AKT | AKT | 0.0533 | uM | 7463.074 | 0.7348 | 0.0195 | 0.4574 | |
| HCC2185 | TNBC | Luminal | Triciribine | AKT | AKT | 0.267 | uM | 7463.074 | 0.6770 | -0.1476 | 0.4574 | |
| HCC2185 | TNBC | Luminal | Triciribine | AKT | AKT | 1.33 | uM | 7463.074 | 0.5820 | -0.3876 | 0.4574 | |
| HCC2185 | TNBC | Luminal | Triciribine | AKT | AKT | 6.67 | uM | 7463.074 | 0.5138 | -0.5336 | 0.4574 | |
| HCC2185 | TNBC | Luminal | Triciribine | AKT | AKT | 33.3 | uM | 7463.074 | 0.4324 | -0.6802 | 0.4574 | |
| HCC2185 | TNBC | Luminal | Triciribine | AKT | AKT | 0.0000853 | uM | 7464.074 | 0.9986 | 0.9949 | 0.5504 | |
| HCC2185 | TNBC | Luminal | Triciribine | AKT | AKT | 0.000427 | uM | 7464.074 | 1.0579 | 1.2152 | 0.5504 | |
| HCC2185 | TNBC | Luminal | Triciribine | AKT | AKT | 0.00213 | uM | 7464.074 | 0.9827 | 0.9374 | 0.5504 | |
| HCC2185 | TNBC | Luminal | Triciribine | AKT | AKT | 0.0107 | uM | 7464.074 | 0.9181 | 0.7123 | 0.5504 | |
| HCC2185 | TNBC | Luminal | Triciribine | AKT | AKT | 0.0533 | uM | 7464.074 | 0.7989 | 0.3302 | 0.5504 | |
| HCC2185 | TNBC | Luminal | Triciribine | AKT | AKT | 0.267 | uM | 7464.074 | 0.6906 | 0.0207 | 0.5504 | |
| HCC2185 | TNBC | Luminal | Triciribine | AKT | AKT | 1.33 | uM | 7464.074 | 0.6405 | -0.1097 | 0.5504 | |
| HCC2185 | TNBC | Luminal | Triciribine | AKT | AKT | 6.67 | uM | 7464.074 | 0.5614 | -0.2994 | 0.5504 | |
| HCC2185 | TNBC | Luminal | Triciribine | AKT | AKT | 33.3 | uM | 7464.074 | 0.4757 | -0.4814 | 0.5504 | |
| HCC3153 | TNBC | Basal A | Triciribine | AKT | AKT | 0.0000853 | uM | 7466.074 | 0.9382 | 0.8730 | 0.9724 | |
| HCC3153 | TNBC | Basal A | Triciribine | AKT | AKT | 0.000427 | uM | 7466.074 | 0.9942 | 0.9881 | 0.9724 | |
| HCC3153 | TNBC | Basal A | Triciribine | AKT | AKT | 0.00213 | uM | 7466.074 | 0.9406 | 0.8779 | 0.9724 |