Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
BT-474	HER2amp	Luminal	Triciribine	AKT	AKT	6.67	uM	5906.074	0.5405	-0.2304	0.6442
BT-474	HER2amp	Luminal	Triciribine	AKT	AKT	33.3	uM	5906.074	0.5092	-0.2986	0.6442
BT-483	HR+	Luminal	Triciribine	AKT	AKT	0.0000853	uM	5908.074	0.9507	0.8154	0.5224
BT-483	HR+	Luminal	Triciribine	AKT	AKT	0.000427	uM	5908.074	0.9173	0.6954	0.5224
BT-483	HR+	Luminal	Triciribine	AKT	AKT	0.00213	uM	5908.074	0.9576	0.8407	0.5224
BT-483	HR+	Luminal	Triciribine	AKT	AKT	0.0107	uM	5908.074	0.9133	0.6811	0.5224
BT-483	HR+	Luminal	Triciribine	AKT	AKT	0.0533	uM	5908.074	0.7880	0.2676	0.5224
BT-483	HR+	Luminal	Triciribine	AKT	AKT	0.267	uM	5908.074	0.7286	0.0909	0.5224
BT-483	HR+	Luminal	Triciribine	AKT	AKT	1.33	uM	5908.074	0.6872	-0.0247	0.5224
BT-483	HR+	Luminal	Triciribine	AKT	AKT	6.67	uM	5908.074	0.6288	-0.1772	0.5224
BT-483	HR+	Luminal	Triciribine	AKT	AKT	33.3	uM	5908.074	0.5544	-0.3535	0.5224
BT-549	TNBC	Basal B	Triciribine	AKT	AKT	0.0000853	uM	5909.074	0.9499	0.9644	2.8598
BT-549	TNBC	Basal B	Triciribine	AKT	AKT	0.000427	uM	5909.074	1.0863	1.0587	2.8598
BT-549	TNBC	Basal B	Triciribine	AKT	AKT	0.00213	uM	5909.074	0.9655	0.9756	2.8598
BT-549	TNBC	Basal B	Triciribine	AKT	AKT	0.0107	uM	5909.074	1.0766	1.0523	2.8598
BT-549	TNBC	Basal B	Triciribine	AKT	AKT	0.0533	uM	5909.074	1.1136	1.0767	2.8598
BT-549	TNBC	Basal B	Triciribine	AKT	AKT	0.267	uM	5909.074	1.0198	1.0138	2.8598
BT-549	TNBC	Basal B	Triciribine	AKT	AKT	1.33	uM	5909.074	0.0440	-0.3291	2.8598
BT-549	TNBC	Basal B	Triciribine	AKT	AKT	6.67	uM	5909.074	0.8552	0.8935	2.8598
BT-549	TNBC	Basal B	Triciribine	AKT	AKT	33.3	uM	5909.074	0.7442	0.8037	2.8598
BT-549	TNBC	Basal B	Triciribine	AKT	AKT	0.0000853	uM	5910.074	0.9712	0.9819	3.2172
BT-549	TNBC	Basal B	Triciribine	AKT	AKT	0.000427	uM	5910.074	0.9773	0.9858	3.2172
BT-549	TNBC	Basal B	Triciribine	AKT	AKT	0.00213	uM	5910.074	0.9756	0.9847	3.2172
BT-549	TNBC	Basal B	Triciribine	AKT	AKT	0.0107	uM	5910.074	0.9994	0.9996	3.2172
BT-549	TNBC	Basal B	Triciribine	AKT	AKT	0.0533	uM	5910.074	0.9798	0.9874	3.2172

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)