Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
BT-20
TNBC
Basal A
Triciribine
AKT
AKT
0.0000853
uM
5904.074
0.9677 0.9331 0.9654
BT-20
TNBC
Basal A
Triciribine
AKT
AKT
0.000427
uM
5904.074
0.9803 0.9592 0.9654
BT-20
TNBC
Basal A
Triciribine
AKT
AKT
0.00213
uM
5904.074
0.9267 0.8484 0.9654
BT-20
TNBC
Basal A
Triciribine
AKT
AKT
0.0107
uM
5904.074
1.0094 1.0194 0.9654
BT-20
TNBC
Basal A
Triciribine
AKT
AKT
0.0533
uM
5904.074
1.0315 1.0654 0.9654
BT-20
TNBC
Basal A
Triciribine
AKT
AKT
0.267
uM
5904.074
0.8219 0.6324 0.9654
BT-20
TNBC
Basal A
Triciribine
AKT
AKT
1.33
uM
5904.074
0.6238 0.2266 0.9654
BT-20
TNBC
Basal A
Triciribine
AKT
AKT
6.67
uM
5904.074
0.5576 0.0921 0.9654
BT-20
TNBC
Basal A
Triciribine
AKT
AKT
33.3
uM
5904.074
0.4035 -0.2190 0.9654
BT-474
HER2amp
Luminal
Triciribine
AKT
AKT
0.0000853
uM
5905.074
0.9845 0.9642 0.8648
BT-474
HER2amp
Luminal
Triciribine
AKT
AKT
0.000427
uM
5905.074
0.9821 0.9586 0.8648
BT-474
HER2amp
Luminal
Triciribine
AKT
AKT
0.00213
uM
5905.074
0.9282 0.8349 0.8648
BT-474
HER2amp
Luminal
Triciribine
AKT
AKT
0.0107
uM
5905.074
0.8965 0.7627 0.8648
BT-474
HER2amp
Luminal
Triciribine
AKT
AKT
0.0533
uM
5905.074
0.8356 0.6248 0.8648
BT-474
HER2amp
Luminal
Triciribine
AKT
AKT
0.267
uM
5905.074
0.7192 0.3662 0.8648
BT-474
HER2amp
Luminal
Triciribine
AKT
AKT
1.33
uM
5905.074
0.3684 -0.3698 0.8648
BT-474
HER2amp
Luminal
Triciribine
AKT
AKT
6.67
uM
5905.074
0.5048 -0.0927 0.8648
BT-474
HER2amp
Luminal
Triciribine
AKT
AKT
33.3
uM
5905.074
0.4199 -0.2667 0.8648
BT-474
HER2amp
Luminal
Triciribine
AKT
AKT
0.0000853
uM
5906.074
1.0186 1.0582 0.6442
BT-474
HER2amp
Luminal
Triciribine
AKT
AKT
0.000427
uM
5906.074
1.0117 1.0364 0.6442
BT-474
HER2amp
Luminal
Triciribine
AKT
AKT
0.00213
uM
5906.074
1.0583 1.1839 0.6442
BT-474
HER2amp
Luminal
Triciribine
AKT
AKT
0.0107
uM
5906.074
0.7444 0.2648 0.6442
BT-474
HER2amp
Luminal
Triciribine
AKT
AKT
0.0533
uM
5906.074
0.7377 0.2472 0.6442
BT-474
HER2amp
Luminal
Triciribine
AKT
AKT
0.267
uM
5906.074
0.7139 0.1853 0.6442
BT-474
HER2amp
Luminal
Triciribine
AKT
AKT
1.33
uM
5906.074
0.6440 0.0102 0.6442