Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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BT-20 | TNBC | Basal A | Triciribine | AKT | AKT | 0.0000853 | uM | 5904.074 | 0.9677 | 0.9331 | 0.9654 | |
BT-20 | TNBC | Basal A | Triciribine | AKT | AKT | 0.000427 | uM | 5904.074 | 0.9803 | 0.9592 | 0.9654 | |
BT-20 | TNBC | Basal A | Triciribine | AKT | AKT | 0.00213 | uM | 5904.074 | 0.9267 | 0.8484 | 0.9654 | |
BT-20 | TNBC | Basal A | Triciribine | AKT | AKT | 0.0107 | uM | 5904.074 | 1.0094 | 1.0194 | 0.9654 | |
BT-20 | TNBC | Basal A | Triciribine | AKT | AKT | 0.0533 | uM | 5904.074 | 1.0315 | 1.0654 | 0.9654 | |
BT-20 | TNBC | Basal A | Triciribine | AKT | AKT | 0.267 | uM | 5904.074 | 0.8219 | 0.6324 | 0.9654 | |
BT-20 | TNBC | Basal A | Triciribine | AKT | AKT | 1.33 | uM | 5904.074 | 0.6238 | 0.2266 | 0.9654 | |
BT-20 | TNBC | Basal A | Triciribine | AKT | AKT | 6.67 | uM | 5904.074 | 0.5576 | 0.0921 | 0.9654 | |
BT-20 | TNBC | Basal A | Triciribine | AKT | AKT | 33.3 | uM | 5904.074 | 0.4035 | -0.2190 | 0.9654 | |
BT-474 | HER2amp | Luminal | Triciribine | AKT | AKT | 0.0000853 | uM | 5905.074 | 0.9845 | 0.9642 | 0.8648 | |
BT-474 | HER2amp | Luminal | Triciribine | AKT | AKT | 0.000427 | uM | 5905.074 | 0.9821 | 0.9586 | 0.8648 | |
BT-474 | HER2amp | Luminal | Triciribine | AKT | AKT | 0.00213 | uM | 5905.074 | 0.9282 | 0.8349 | 0.8648 | |
BT-474 | HER2amp | Luminal | Triciribine | AKT | AKT | 0.0107 | uM | 5905.074 | 0.8965 | 0.7627 | 0.8648 | |
BT-474 | HER2amp | Luminal | Triciribine | AKT | AKT | 0.0533 | uM | 5905.074 | 0.8356 | 0.6248 | 0.8648 | |
BT-474 | HER2amp | Luminal | Triciribine | AKT | AKT | 0.267 | uM | 5905.074 | 0.7192 | 0.3662 | 0.8648 | |
BT-474 | HER2amp | Luminal | Triciribine | AKT | AKT | 1.33 | uM | 5905.074 | 0.3684 | -0.3698 | 0.8648 | |
BT-474 | HER2amp | Luminal | Triciribine | AKT | AKT | 6.67 | uM | 5905.074 | 0.5048 | -0.0927 | 0.8648 | |
BT-474 | HER2amp | Luminal | Triciribine | AKT | AKT | 33.3 | uM | 5905.074 | 0.4199 | -0.2667 | 0.8648 | |
BT-474 | HER2amp | Luminal | Triciribine | AKT | AKT | 0.0000853 | uM | 5906.074 | 1.0186 | 1.0582 | 0.6442 | |
BT-474 | HER2amp | Luminal | Triciribine | AKT | AKT | 0.000427 | uM | 5906.074 | 1.0117 | 1.0364 | 0.6442 | |
BT-474 | HER2amp | Luminal | Triciribine | AKT | AKT | 0.00213 | uM | 5906.074 | 1.0583 | 1.1839 | 0.6442 | |
BT-474 | HER2amp | Luminal | Triciribine | AKT | AKT | 0.0107 | uM | 5906.074 | 0.7444 | 0.2648 | 0.6442 | |
BT-474 | HER2amp | Luminal | Triciribine | AKT | AKT | 0.0533 | uM | 5906.074 | 0.7377 | 0.2472 | 0.6442 | |
BT-474 | HER2amp | Luminal | Triciribine | AKT | AKT | 0.267 | uM | 5906.074 | 0.7139 | 0.1853 | 0.6442 | |
BT-474 | HER2amp | Luminal | Triciribine | AKT | AKT | 1.33 | uM | 5906.074 | 0.6440 | 0.0102 | 0.6442 |