Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10996.072 | 1.0096 | 1.0317 | 0.6093 | |
| HCC2185 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10996.072 | 0.9748 | 0.9179 | 0.6093 | |
| HCC2185 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10996.072 | 0.9775 | 0.9266 | 0.6093 | |
| HCC2185 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10996.072 | 0.9351 | 0.7916 | 0.6093 | |
| HCC2185 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10996.072 | 0.9231 | 0.7539 | 0.6093 | |
| HCC2185 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10996.072 | 0.6899 | 0.0876 | 0.6093 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7465.072 | 1.0342 | 1.0505 | 1.3502 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7465.072 | 0.9570 | 0.9359 | 1.3502 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7465.072 | 1.0048 | 1.0071 | 1.3502 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7465.072 | 0.9960 | 0.9941 | 1.3502 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7465.072 | 1.0318 | 1.0469 | 1.3502 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7465.072 | 0.9697 | 0.9550 | 1.3502 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7465.072 | 0.8514 | 0.7754 | 1.3502 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7465.072 | 0.6154 | 0.3960 | 1.3502 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7465.072 | 0.4612 | 0.1274 | 1.3502 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7466.072 | 1.0478 | 1.1324 | 0.7283 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7466.072 | 1.0024 | 1.0066 | 0.7283 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7466.072 | 1.0352 | 1.0972 | 0.7283 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7466.072 | 1.0095 | 1.0262 | 0.7283 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7466.072 | 0.9812 | 0.9486 | 0.7283 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7466.072 | 1.0224 | 1.0617 | 0.7283 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7466.072 | 0.9559 | 0.8798 | 0.7283 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7466.072 | 0.5697 | -0.0765 | 0.7283 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7466.072 | 0.4427 | -0.3467 | 0.7283 | |
| HCC3153 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10577.072 | 1.0071 | 1.0145 | 0.9803 |