Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10469.072 | 0.9649 | 0.9475 | 1.3439 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10469.072 | 1.0285 | 1.0422 | 1.3439 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10469.072 | 0.9989 | 0.9983 | 1.3439 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10469.072 | 0.6680 | 0.4813 | 1.3439 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 11055.072 | 0.9941 | 0.9934 | 1.7997 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 11055.072 | 0.9018 | 0.8884 | 1.7997 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 11055.072 | 0.9559 | 0.9505 | 1.7997 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 11055.072 | 0.9313 | 0.9224 | 1.7997 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 11055.072 | 0.9253 | 0.9155 | 1.7997 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 11055.072 | 0.9358 | 0.9276 | 1.7997 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 11055.072 | 0.9579 | 0.9528 | 1.7997 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 11055.072 | 0.9556 | 0.9501 | 1.7997 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 11055.072 | 0.8568 | 0.8354 | 1.7997 | |
| HCC202 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10470.072 | 1.0276 | 1.1720 | 0.3299 | |
| HCC202 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10470.072 | 1.0000 | 1.0000 | 0.3299 | |
| HCC202 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10470.072 | 1.0094 | 1.0576 | 0.3299 | |
| HCC202 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10470.072 | 1.0386 | 1.2432 | 0.3299 | |
| HCC202 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10470.072 | 1.0077 | 1.0471 | 0.3299 | |
| HCC202 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10470.072 | 0.9689 | 0.8175 | 0.3299 | |
| HCC202 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10470.072 | 0.9849 | 0.9100 | 0.3299 | |
| HCC202 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10470.072 | 0.9783 | 0.8712 | 0.3299 | |
| HCC202 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10470.072 | 0.4627 | -0.8066 | 0.3299 | |
| HCC2185 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10996.072 | 0.9650 | 0.8864 | 0.6093 | |
| HCC2185 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10996.072 | 0.9196 | 0.7430 | 0.6093 | |
| HCC2185 | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10996.072 | 0.9702 | 0.9032 | 0.6093 |