Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 600MPE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 12224.072 | 0.9394 | 0.8799 | 1.0105 | |
| 600MPE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 12224.072 | 0.8924 | 0.7869 | 1.0105 | |
| 600MPE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 12224.072 | 0.9826 | 0.9656 | 1.0105 | |
| 600MPE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 12224.072 | 0.8949 | 0.7918 | 1.0105 | |
| 600MPE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 12224.072 | 0.9638 | 0.9284 | 1.0105 | |
| 600MPE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 12224.072 | 0.9686 | 0.9379 | 1.0105 | |
| 600MPE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 12224.072 | 0.9216 | 0.8447 | 1.0105 | |
| 600MPE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 12224.072 | 0.9233 | 0.8481 | 1.0105 | |
| 600MPE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 12224.072 | 0.9166 | 0.8349 | 1.0105 | |
| AU565 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 5900.072 | 1.0524 | 1.0410 | 2.5162 | |
| AU565 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 5900.072 | 0.9704 | 0.9763 | 2.5162 | |
| AU565 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 5900.072 | 0.9399 | 0.9513 | 2.5162 | |
| AU565 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 5900.072 | 0.9974 | 0.9980 | 2.5162 | |
| AU565 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 5900.072 | 0.9802 | 0.9842 | 2.5162 | |
| AU565 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 5900.072 | 0.8880 | 0.9078 | 2.5162 | |
| AU565 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 5900.072 | 0.9786 | 0.9829 | 2.5162 | |
| AU565 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 5900.072 | 0.6478 | 0.6830 | 2.5162 | |
| AU565 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 5900.072 | 0.0829 | -0.2566 | 2.5162 | |
| AU565 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10880.072 | 0.9294 | 0.9115 | 1.6177 | |
| AU565 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10880.072 | 1.0010 | 1.0012 | 1.6177 | |
| AU565 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10880.072 | 0.9818 | 0.9774 | 1.6177 | |
| AU565 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10880.072 | 1.0571 | 1.0699 | 1.6177 | |
| AU565 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10880.072 | 0.9928 | 0.9910 | 1.6177 | |
| AU565 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10880.072 | 0.9854 | 0.9819 | 1.6177 | |
| AU565 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10880.072 | 0.8579 | 0.8192 | 1.6177 |