Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184A1 | NM | Basal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 5895.073 | 1.0510 | 1.0702 | 1.4431 | |
| 184A1 | NM | Basal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 5895.073 | 1.0544 | 1.0748 | 1.4431 | |
| 184A1 | NM | Basal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 5895.073 | 1.0313 | 1.0432 | 1.4431 | |
| 184A1 | NM | Basal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 5895.073 | 1.0070 | 1.0098 | 1.4431 | |
| 184A1 | NM | Basal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 5895.073 | 0.9893 | 0.9851 | 1.4431 | |
| 184A1 | NM | Basal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 5895.073 | 0.8615 | 0.8038 | 1.4431 | |
| 184A1 | NM | Basal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 5895.073 | 0.7240 | 0.5990 | 1.4431 | |
| 184B5 | NM | Basal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 5897.073 | 1.0284 | 1.0460 | 1.2323 | |
| 184B5 | NM | Basal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 5897.073 | 1.0177 | 1.0286 | 1.2323 | |
| 184B5 | NM | Basal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 5897.073 | 0.9997 | 0.9994 | 1.2323 | |
| 184B5 | NM | Basal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 5897.073 | 0.9879 | 0.9803 | 1.2323 | |
| 184B5 | NM | Basal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 5897.073 | 0.9966 | 0.9944 | 1.2323 | |
| 184B5 | NM | Basal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 5897.073 | 1.0141 | 1.0229 | 1.2323 | |
| 184B5 | NM | Basal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 5897.073 | 1.0228 | 1.0370 | 1.2323 | |
| 184B5 | NM | Basal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 5897.073 | 1.0296 | 1.0480 | 1.2323 | |
| 184B5 | NM | Basal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 5897.073 | 0.8419 | 0.7393 | 1.2323 | |
| 600MPE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 5898.073 | 1.0008 | 1.0024 | 0.6501 | |
| 600MPE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 5898.073 | 0.9517 | 0.8535 | 0.6501 | |
| 600MPE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 5898.073 | 0.9763 | 0.9276 | 0.6501 | |
| 600MPE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 5898.073 | 1.0129 | 1.0398 | 0.6501 | |
| 600MPE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 5898.073 | 0.9962 | 0.9883 | 0.6501 | |
| 600MPE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 5898.073 | 0.9306 | 0.7904 | 0.6501 | |
| 600MPE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 5898.073 | 1.0135 | 1.0416 | 0.6501 | |
| 600MPE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 5898.073 | 0.9603 | 0.8792 | 0.6501 | |
| 600MPE | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 5898.073 | 0.8194 | 0.4721 | 0.6501 |