Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
SK-BR-3	HER2amp	Luminal	AG1478	EGFR	ErbB	0.267	uM	9759.019	0.9810	0.9722	1.3677
SK-BR-3	HER2amp	Luminal	AG1478	EGFR	ErbB	1.33	uM	9759.019	0.9099	0.8666	1.3677
SK-BR-3	HER2amp	Luminal	AG1478	EGFR	ErbB	6.67	uM	9759.019	0.4600	0.1335	1.3677
SK-BR-3	HER2amp	Luminal	AG1478	EGFR	ErbB	33.3	uM	9759.019	0.8853	0.8295	1.3677
SK-BR-3	HER2amp	Luminal	AG1478	EGFR	ErbB	167	uM	9759.019	0.4459	0.1080	1.3677
SUM1315MO2	TNBC	Basal B	AG1478	EGFR	ErbB	0.000427	uM	7529.016	1.0136	1.0467	0.5847
SUM1315MO2	TNBC	Basal B	AG1478	EGFR	ErbB	0.00213	uM	7529.016	1.0230	1.0792	0.5847
SUM1315MO2	TNBC	Basal B	AG1478	EGFR	ErbB	0.0107	uM	7529.016	0.9619	0.8714	0.5847
SUM1315MO2	TNBC	Basal B	AG1478	EGFR	ErbB	0.0533	uM	7529.016	0.9609	0.8679	0.5847
SUM1315MO2	TNBC	Basal B	AG1478	EGFR	ErbB	0.267	uM	7529.016	0.9327	0.7752	0.5847
SUM1315MO2	TNBC	Basal B	AG1478	EGFR	ErbB	1.33	uM	7529.016	0.8737	0.5877	0.5847
SUM1315MO2	TNBC	Basal B	AG1478	EGFR	ErbB	6.67	uM	7529.016	0.8591	0.5425	0.5847
SUM1315MO2	TNBC	Basal B	AG1478	EGFR	ErbB	33.3	uM	7529.016	0.6702	0.0087	0.5847
SUM1315MO2	TNBC	Basal B	AG1478	EGFR	ErbB	167	uM	7529.016	0.7402	0.1957	0.5847
SUM1315MO2	TNBC	Basal B	AG1478	EGFR	ErbB	0.000427	uM	9797.019	0.9609	0.8440	0.4912
SUM1315MO2	TNBC	Basal B	AG1478	EGFR	ErbB	0.00213	uM	9797.019	0.9878	0.9505	0.4912
SUM1315MO2	TNBC	Basal B	AG1478	EGFR	ErbB	0.0107	uM	9797.019	0.9553	0.8222	0.4912
SUM1315MO2	TNBC	Basal B	AG1478	EGFR	ErbB	0.0533	uM	9797.019	0.9335	0.7384	0.4912
SUM1315MO2	TNBC	Basal B	AG1478	EGFR	ErbB	0.267	uM	9797.019	0.7944	0.2519	0.4912
SUM1315MO2	TNBC	Basal B	AG1478	EGFR	ErbB	1.33	uM	9797.019	0.7302	0.0544	0.4912
SUM1315MO2	TNBC	Basal B	AG1478	EGFR	ErbB	6.67	uM	9797.019	0.7108	-0.0016	0.4912
SUM1315MO2	TNBC	Basal B	AG1478	EGFR	ErbB	33.3	uM	9797.019	0.7418	0.0890	0.4912
SUM1315MO2	TNBC	Basal B	AG1478	EGFR	ErbB	167	uM	9797.019	0.7048	-0.0189	0.4912
SUM149PT	TNBC	Basal B	AG1478	EGFR	ErbB	0.000427	uM	7917.016	0.9667	0.9772	2.9532
SUM149PT	TNBC	Basal B	AG1478	EGFR	ErbB	0.00213	uM	7917.016	1.0289	1.0194	2.9532

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)