Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.267 | uM | 7874.016 | 0.8909 | 0.8602 | 1.5947 | |
| MCF7 | HR+ | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 7874.016 | 0.9345 | 0.9168 | 1.5947 | |
| MCF7 | HR+ | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 7874.016 | 1.0041 | 1.0051 | 1.5947 | |
| MCF7 | HR+ | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 7874.016 | 0.8915 | 0.8611 | 1.5947 | |
| MCF7 | HR+ | Luminal | AG1478 | EGFR | ErbB | 167 | uM | 7874.016 | 0.6188 | 0.4802 | 1.5947 | |
| MCF7 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.000427 | uM | 7875.016 | 0.9832 | 0.9793 | 1.6229 | |
| MCF7 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.00213 | uM | 7875.016 | 0.9429 | 0.9289 | 1.6229 | |
| MCF7 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.0107 | uM | 7875.016 | 0.9865 | 0.9834 | 1.6229 | |
| MCF7 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.0533 | uM | 7875.016 | 0.9297 | 0.9122 | 1.6229 | |
| MCF7 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.267 | uM | 7875.016 | 0.9690 | 0.9615 | 1.6229 | |
| MCF7 | HR+ | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 7875.016 | 0.9717 | 0.9650 | 1.6229 | |
| MCF7 | HR+ | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 7875.016 | 0.9724 | 0.9658 | 1.6229 | |
| MCF7 | HR+ | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 7875.016 | 0.9919 | 0.9900 | 1.6229 | |
| MCF7 | HR+ | Luminal | AG1478 | EGFR | ErbB | 167 | uM | 7875.016 | 0.9023 | 0.8772 | 1.6229 | |
| MDA-MB-134-VI | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.000427 | uM | 7876.016 | 1.0128 | 1.0242 | 1.0580 | |
| MDA-MB-134-VI | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.00213 | uM | 7876.016 | 0.9989 | 0.9979 | 1.0580 | |
| MDA-MB-134-VI | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.0107 | uM | 7876.016 | 0.9936 | 0.9879 | 1.0580 | |
| MDA-MB-134-VI | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.0533 | uM | 7876.016 | 0.9612 | 0.9266 | 1.0580 | |
| MDA-MB-134-VI | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.267 | uM | 7876.016 | 0.9972 | 0.9948 | 1.0580 | |
| MDA-MB-134-VI | HR+ | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 7876.016 | 1.0508 | 1.0959 | 1.0580 | |
| MDA-MB-134-VI | HR+ | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 7876.016 | 0.9790 | 0.9603 | 1.0580 | |
| MDA-MB-134-VI | HR+ | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 7876.016 | 0.9183 | 0.8452 | 1.0580 | |
| MDA-MB-134-VI | HR+ | Luminal | AG1478 | EGFR | ErbB | 167 | uM | 7876.016 | 0.7888 | 0.5982 | 1.0580 | |
| MDA-MB-157 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.000427 | uM | 7878.016 | 1.0085 | 1.0120 | 1.4153 | |
| MDA-MB-157 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.00213 | uM | 7878.016 | 0.9554 | 0.9366 | 1.4153 |