Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-157 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.121 | uM | 7498.065 | 0.9729 | 0.9540 | 1.1827 | |
| MDA-MB-157 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.606 | uM | 7498.065 | 0.9631 | 0.9374 | 1.1827 | |
| MDA-MB-157 | TNBC | Basal B | PS-1145 | IKK | NFKB | 3.03 | uM | 7498.065 | 1.0164 | 1.0277 | 1.1827 | |
| MDA-MB-157 | TNBC | Basal B | PS-1145 | IKK | NFKB | 15.2 | uM | 7498.065 | 0.9493 | 0.9139 | 1.1827 | |
| MDA-MB-157 | TNBC | Basal B | PS-1145 | IKK | NFKB | 75.8 | uM | 7498.065 | 0.9769 | 0.9608 | 1.1827 | |
| MDA-MB-157 | TNBC | Basal B | PS-1145 | IKK | NFKB | 379 | uM | 7498.065 | 0.9306 | 0.8821 | 1.1827 | |
| MDA-MB-157 | TNBC | Basal B | PS-1145 | IKK | NFKB | 1890 | uM | 7498.065 | 0.9027 | 0.8341 | 1.1827 | |
| MDA-MB-175-VII | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.00485 | uM | 7499.065 | 1.0306 | 1.1144 | 0.5419 | |
| MDA-MB-175-VII | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.0243 | uM | 7499.065 | 0.9991 | 0.9966 | 0.5419 | |
| MDA-MB-175-VII | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.121 | uM | 7499.065 | 1.0266 | 1.0993 | 0.5419 | |
| MDA-MB-175-VII | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.606 | uM | 7499.065 | 1.0219 | 1.0816 | 0.5419 | |
| MDA-MB-175-VII | HR+ | Luminal | PS-1145 | IKK | NFKB | 3.03 | uM | 7499.065 | 0.9661 | 0.8765 | 0.5419 | |
| MDA-MB-175-VII | HR+ | Luminal | PS-1145 | IKK | NFKB | 15.2 | uM | 7499.065 | 0.9546 | 0.8355 | 0.5419 | |
| MDA-MB-175-VII | HR+ | Luminal | PS-1145 | IKK | NFKB | 75.8 | uM | 7499.065 | 0.9805 | 0.9286 | 0.5419 | |
| MDA-MB-175-VII | HR+ | Luminal | PS-1145 | IKK | NFKB | 379 | uM | 7499.065 | 0.8690 | 0.5436 | 0.5419 | |
| MDA-MB-175-VII | HR+ | Luminal | PS-1145 | IKK | NFKB | 1890 | uM | 7499.065 | 0.8424 | 0.4575 | 0.5419 | |
| MDA-MB-175-VII | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.00485 | uM | 7500.065 | 0.9286 | 0.8273 | 0.8201 | |
| MDA-MB-175-VII | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.0243 | uM | 7500.065 | 0.9496 | 0.8779 | 0.8201 | |
| MDA-MB-175-VII | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.121 | uM | 7500.065 | 0.9545 | 0.8896 | 0.8201 | |
| MDA-MB-175-VII | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.606 | uM | 7500.065 | 1.0567 | 1.1392 | 0.8201 | |
| MDA-MB-175-VII | HR+ | Luminal | PS-1145 | IKK | NFKB | 3.03 | uM | 7500.065 | 1.0229 | 1.0559 | 0.8201 | |
| MDA-MB-175-VII | HR+ | Luminal | PS-1145 | IKK | NFKB | 15.2 | uM | 7500.065 | 0.9016 | 0.7626 | 0.8201 | |
| MDA-MB-175-VII | HR+ | Luminal | PS-1145 | IKK | NFKB | 75.8 | uM | 7500.065 | 0.9919 | 0.9802 | 0.8201 | |
| MDA-MB-175-VII | HR+ | Luminal | PS-1145 | IKK | NFKB | 379 | uM | 7500.065 | 0.8938 | 0.7441 | 0.8201 | |
| MDA-MB-175-VII | HR+ | Luminal | PS-1145 | IKK | NFKB | 1890 | uM | 7500.065 | 0.8276 | 0.5879 | 0.8201 |