Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-415 | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 117 | uM | 7511.095 | 0.8138 | 0.6737 | 1.1565 | |
| MDA-MB-415 | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 585 | uM | 7511.095 | 0.7757 | 0.6055 | 1.1565 | |
| MDA-MB-415 | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 2920 | uM | 7511.095 | 0.8083 | 0.6638 | 1.1565 | |
| MDA-MB-415 | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.00749 | uM | 7512.095 | 0.8998 | 0.7651 | 0.8452 | |
| MDA-MB-415 | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.0374 | uM | 7512.095 | 0.9971 | 0.9930 | 0.8452 | |
| MDA-MB-415 | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.187 | uM | 7512.095 | 0.9891 | 0.9743 | 0.8452 | |
| MDA-MB-415 | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.936 | uM | 7512.095 | 0.9431 | 0.8661 | 0.8452 | |
| MDA-MB-415 | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 4.68 | uM | 7512.095 | 0.9467 | 0.8746 | 0.8452 | |
| MDA-MB-415 | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 23.4 | uM | 7512.095 | 1.0151 | 1.0359 | 0.8452 | |
| MDA-MB-415 | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 117 | uM | 7512.095 | 0.9797 | 0.9521 | 0.8452 | |
| MDA-MB-415 | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 585 | uM | 7512.095 | 0.9258 | 0.8257 | 0.8452 | |
| MDA-MB-415 | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 2920 | uM | 7512.095 | 1.0060 | 1.0142 | 0.8452 | |
| MDA-MB-453 | TNBC | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.00749 | uM | 7515.095 | 0.8811 | 0.7537 | 0.9628 | |
| MDA-MB-453 | TNBC | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.0374 | uM | 7515.095 | 0.7593 | 0.5026 | 0.9628 | |
| MDA-MB-453 | TNBC | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.187 | uM | 7515.095 | 0.8438 | 0.6766 | 0.9628 | |
| MDA-MB-453 | TNBC | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.936 | uM | 7515.095 | 0.8170 | 0.6213 | 0.9628 | |
| MDA-MB-453 | TNBC | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 4.68 | uM | 7515.095 | 0.8675 | 0.7255 | 0.9628 | |
| MDA-MB-453 | TNBC | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 23.4 | uM | 7515.095 | 0.7562 | 0.4962 | 0.9628 | |
| MDA-MB-453 | TNBC | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 117 | uM | 7515.095 | 0.8313 | 0.6508 | 0.9628 | |
| MDA-MB-453 | TNBC | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 585 | uM | 7515.095 | 0.7487 | 0.4808 | 0.9628 | |
| MDA-MB-453 | TNBC | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 2920 | uM | 7515.095 | 0.7331 | 0.4487 | 0.9628 | |
| MDA-MB-453 | TNBC | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.00749 | uM | 7516.095 | 0.9028 | 0.8534 | 1.3423 | |
| MDA-MB-453 | TNBC | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.0374 | uM | 7516.095 | 0.9137 | 0.8700 | 1.3423 | |
| MDA-MB-453 | TNBC | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.187 | uM | 7516.095 | 0.9251 | 0.8873 | 1.3423 | |
| MDA-MB-453 | TNBC | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.936 | uM | 7516.095 | 0.8994 | 0.8481 | 1.3423 |