Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | PD184352 | MEK | MAPK | 13.3 | uM | 10694.146 | 0.8368 | 0.8498 | 2.2821 | |
| Hs 578T | TNBC | Basal B | PD184352 | MEK | MAPK | 13.3 | uM | 10694.146 | 0.8368 | 0.8498 | 2.2821 | |
| Hs 578T | TNBC | Basal B | PD184352 | MEK | MAPK | 66.7 | uM | 10694.146 | 0.6921 | 0.7021 | 2.2821 | |
| Hs 578T | TNBC | Basal B | PD184352 | MEK | MAPK | 66.7 | uM | 10694.146 | 0.6921 | 0.7021 | 2.2821 | |
| LY2 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0000853 | uM | 10816.155 | 1.1008 | 1.2436 | 0.8353 | |
| LY2 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0000853 | uM | 10816.155 | 1.1008 | 1.2436 | 0.8353 | |
| LY2 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.000427 | uM | 10816.155 | 1.1894 | 1.4616 | 0.8353 | |
| LY2 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.000427 | uM | 10816.155 | 1.1894 | 1.4616 | 0.8353 | |
| LY2 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.00213 | uM | 10816.155 | 1.0790 | 1.1905 | 0.8353 | |
| LY2 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.00213 | uM | 10816.155 | 1.0790 | 1.1905 | 0.8353 | |
| LY2 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0107 | uM | 10816.155 | 1.0398 | 1.0957 | 0.8353 | |
| LY2 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0107 | uM | 10816.155 | 1.0398 | 1.0957 | 0.8353 | |
| LY2 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0533 | uM | 10816.155 | 0.8766 | 0.7082 | 0.8353 | |
| LY2 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0533 | uM | 10816.155 | 0.8766 | 0.7082 | 0.8353 | |
| LY2 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.267 | uM | 10816.155 | 1.0372 | 1.0895 | 0.8353 | |
| LY2 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.267 | uM | 10816.155 | 1.0372 | 1.0895 | 0.8353 | |
| LY2 | HR+ | Luminal | PD184352 | MEK | MAPK | 1.33 | uM | 10816.155 | 0.8257 | 0.5902 | 0.8353 | |
| LY2 | HR+ | Luminal | PD184352 | MEK | MAPK | 1.33 | uM | 10816.155 | 0.8257 | 0.5902 | 0.8353 | |
| LY2 | HR+ | Luminal | PD184352 | MEK | MAPK | 6.67 | uM | 10816.155 | 0.9723 | 0.9339 | 0.8353 | |
| LY2 | HR+ | Luminal | PD184352 | MEK | MAPK | 6.67 | uM | 10816.155 | 0.9723 | 0.9339 | 0.8353 | |
| LY2 | HR+ | Luminal | PD184352 | MEK | MAPK | 33.3 | uM | 10816.155 | 0.8045 | 0.5413 | 0.8353 | |
| LY2 | HR+ | Luminal | PD184352 | MEK | MAPK | 33.3 | uM | 10816.155 | 0.8045 | 0.5413 | 0.8353 | |
| LY2 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0000853 | uM | 12319.155 | 1.1222 | 1.2630 | 0.9333 | |
| LY2 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0000853 | uM | 12319.155 | 1.1222 | 1.2630 | 0.9333 | |
| LY2 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.000427 | uM | 12319.155 | 1.0141 | 1.0302 | 0.9333 |