Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.0107 | uM | 12400.155 | 0.9530 | 0.9248 | 1.2558 | |
| HCC70 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.0533 | uM | 12400.155 | 0.9573 | 0.9317 | 1.2558 | |
| HCC70 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.0533 | uM | 12400.155 | 0.9573 | 0.9317 | 1.2558 | |
| HCC70 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.267 | uM | 12400.155 | 0.9244 | 0.8786 | 1.2558 | |
| HCC70 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.267 | uM | 12400.155 | 0.9244 | 0.8786 | 1.2558 | |
| HCC70 | TNBC | Basal A | PD184352 | MEK | MAPK | 1.33 | uM | 12400.155 | 0.9758 | 0.9613 | 1.2558 | |
| HCC70 | TNBC | Basal A | PD184352 | MEK | MAPK | 1.33 | uM | 12400.155 | 0.9758 | 0.9613 | 1.2558 | |
| HCC70 | TNBC | Basal A | PD184352 | MEK | MAPK | 6.67 | uM | 12400.155 | 0.8891 | 0.8213 | 1.2558 | |
| HCC70 | TNBC | Basal A | PD184352 | MEK | MAPK | 6.67 | uM | 12400.155 | 0.8891 | 0.8213 | 1.2558 | |
| HCC70 | TNBC | Basal A | PD184352 | MEK | MAPK | 33.3 | uM | 12400.155 | 0.7277 | 0.5527 | 1.2558 | |
| HCC70 | TNBC | Basal A | PD184352 | MEK | MAPK | 33.3 | uM | 12400.155 | 0.7277 | 0.5527 | 1.2558 | |
| Hs 578T | TNBC | Basal B | PD184352 | MEK | MAPK | 0.000171 | uM | 10694.146 | 0.9699 | 0.9734 | 2.2821 | |
| Hs 578T | TNBC | Basal B | PD184352 | MEK | MAPK | 0.000171 | uM | 10694.146 | 0.9699 | 0.9734 | 2.2821 | |
| Hs 578T | TNBC | Basal B | PD184352 | MEK | MAPK | 0.000853 | uM | 10694.146 | 0.9890 | 0.9903 | 2.2821 | |
| Hs 578T | TNBC | Basal B | PD184352 | MEK | MAPK | 0.000853 | uM | 10694.146 | 0.9890 | 0.9903 | 2.2821 | |
| Hs 578T | TNBC | Basal B | PD184352 | MEK | MAPK | 0.00427 | uM | 10694.146 | 0.9953 | 0.9959 | 2.2821 | |
| Hs 578T | TNBC | Basal B | PD184352 | MEK | MAPK | 0.00427 | uM | 10694.146 | 0.9953 | 0.9959 | 2.2821 | |
| Hs 578T | TNBC | Basal B | PD184352 | MEK | MAPK | 0.0213 | uM | 10694.146 | 1.0295 | 1.0256 | 2.2821 | |
| Hs 578T | TNBC | Basal B | PD184352 | MEK | MAPK | 0.0213 | uM | 10694.146 | 1.0295 | 1.0256 | 2.2821 | |
| Hs 578T | TNBC | Basal B | PD184352 | MEK | MAPK | 0.107 | uM | 10694.146 | 1.0332 | 1.0288 | 2.2821 | |
| Hs 578T | TNBC | Basal B | PD184352 | MEK | MAPK | 0.107 | uM | 10694.146 | 1.0332 | 1.0288 | 2.2821 | |
| Hs 578T | TNBC | Basal B | PD184352 | MEK | MAPK | 0.533 | uM | 10694.146 | 1.0038 | 1.0033 | 2.2821 | |
| Hs 578T | TNBC | Basal B | PD184352 | MEK | MAPK | 0.533 | uM | 10694.146 | 1.0038 | 1.0033 | 2.2821 | |
| Hs 578T | TNBC | Basal B | PD184352 | MEK | MAPK | 2.67 | uM | 10694.146 | 0.9714 | 0.9747 | 2.2821 | |
| Hs 578T | TNBC | Basal B | PD184352 | MEK | MAPK | 2.67 | uM | 10694.146 | 0.9714 | 0.9747 | 2.2821 |